216443-78-6 Usage
Description
3-(3-METHYLPHENYL)BENZALDEHYDE, also known as 3''-Methyl-[1,1''-biphenyl]-3-carbaldehyde, is an organic compound with the molecular formula C14H12O. It is a type of aromatic aldehyde derived from benzene, featuring a methyl group and a phenyl group attached to the benzene ring. 3-(3-METHYLPHENYL)BENZALDEHYDE is known for its distinct chemical properties and reactivity, making it a versatile building block in organic synthesis.
Uses
Used in Organic Synthesis:
3-(3-METHYLPHENYL)BENZALDEHYDE is used as a reagent for the synthesis of various organic compounds, particularly benzoxazoles derivatives and substituted nitrobenzaldehydes. Its unique structure allows it to participate in a range of chemical reactions, such as condensation, reduction, and oxidation, which are essential for creating complex molecular structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(3-METHYLPHENYL)BENZALDEHYDE is utilized as an intermediate in the synthesis of drugs with potential therapeutic applications. Its ability to form diverse chemical structures makes it a valuable component in the development of new medications.
Used in Chemical Research:
3-(3-METHYLPHENYL)BENZALDEHYDE is also employed in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic pathways. Its reactivity and structural features provide valuable insights into the behavior of similar compounds and contribute to the advancement of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 216443-78-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,4,4 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 216443-78:
(8*2)+(7*1)+(6*6)+(5*4)+(4*4)+(3*3)+(2*7)+(1*8)=126
126 % 10 = 6
So 216443-78-6 is a valid CAS Registry Number.
216443-78-6Relevant articles and documents
Scope of the two-step, one-pot palladium-catalyzed borylation/Suzuki cross-coupling reaction utilizing bis-boronic acid
Molander, Gary A.,Trice, Sarah L. J.,Kennedy, Steven M.
, p. 8678 - 8688 (2012/11/07)
The use of bis-boronic acid for the direct synthesis of boronic acids has greatly facilitated the two-step, one-pot borylation/Suzuki cross-coupling reaction between aryl and heteroaryl halides. With use of Buchwald's second-generation XPhos preformed catalyst, high yields of cross-coupled products were obtained for most substrates. The method also allows an efficient two-step, one-pot synthesis, providing access to three distinct cross-coupled products after column chromatography. The method also provides a rapid and convenient route to teraryl compounds.
