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216661-58-4

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216661-58-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 216661-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,6,6 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 216661-58:
(8*2)+(7*1)+(6*6)+(5*6)+(4*6)+(3*1)+(2*5)+(1*8)=134
134 % 10 = 4
So 216661-58-4 is a valid CAS Registry Number.

216661-58-4Relevant articles and documents

Inhibitor of heat shock factor 1, and preparation method and application of inhibitor

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Paragraph 0191; 0205-0206, (2019/12/08)

The invention provides an inhibitor of a heat shock factor 1 (HSF1) and an application of the inhibitor, particularly a compound as shown in a formula I or pharmaceutically-acceptable salt of the compound. The compound has excellent HSF1 restraining activity and tumor resisting effects. The invention further provides a medical composition containing the compound and an application of the medical composition in the respect of restraining HSF1.

INHIBITORS OF THE BMP SIGNALING PATHWAY

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, (2009/10/22)

The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.

Microwave-assisted protocols for the expedited synthesis of pyrazolo[1,5-a] and [3,4-d]pyrimidines

Daniels, R. Nathan,Kim, Kwangho,Lebois, Evan P.,Muchalski, Hubert,Hughes, Mary,Lindsley, Craig W.

, p. 305 - 310 (2008/09/17)

General, high-yielding MAOS protocols for the expedited synthesis of functionalized pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-b]pyrimidines, as well as their pyrazole precursors, are described amenable to an iterative analogue library synthesis strategy for lead optimization.

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