216776-76-0Relevant articles and documents
An easy direct conversion of pyridine- and pyrimidine-thiones into multi-fused heterocyclic compounds
Erian, Ayman Wahba,Abu-Shanab, Fathi Ali
, p. 2387 - 2391 (2007/10/03)
The reaction of azine-thiones with ethyl chlorofluoroacetate afforded 2- fluorothienoazines. The latter underwent self-condensation and gave multi- fused heterocyclic compounds. A wide range of unique heterocycles could be obtained on treatment of 2-fluorothienoazines with nitrogen nucleophilic reagents. The reactivity of the pyrimidine-thiones towards a variety of electrophilic reagents was studied. Chemical and spectroscopic evidence of the newly synthesized compounds are described.