21713-63-3

Basic information

• Product Name: Phosphinic acid, bis(phenylmethyl)-, methyl ester
• CAS NO: 21713-63-3
• Molecular Formula: C15H17O2P
• Molecular Weight: 260.273
• Mol File: 21713-63-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Phosphinic acid, bis(phenylmethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic acid, bis(phenylmethyl)-, methyl ester(21713-63-3)
• EPA Substance Registry System: Phosphinic acid, bis(phenylmethyl)-, methyl ester(21713-63-3)

Safety Data

• Hazardous Substances Data: 21713-63-3(Hazardous Substances Data)

Upstream product

• 1455-13-6 deuteromethanol 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 
• 13238-16-9 dibenzylphosphine oxide 
• 67-56-1 methanol 
• 13398-28-2 1-Brom-2,2-diphenylcyclopropancarbonsaeure-methylester 
• 100-39-0 benzyl bromide 
• 7369-51-9 dibenzylphosphinic acid 
• 74-88-4 methyl iodide 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 1940-57-4 9H-fluoren-9-yl bromide 
• 17201-43-3 4-cyanobenzyl bromide 
• 7705-63-7 1-(bromomethyl)-4-(phenylsulfonyl)benzene 
• 7650-89-7 tribenzylphosphine 
• 76219-39-1 Dibenzylphosphinic acid potassium salt 

Downstream Products

• 1145993-98-1 ((E)-1,2-Diphenyl-vinyl)-phosphonic acid dimethyl ester 
• 36043-90-0 meso-Methyl-α,α'-dibromdibenzylphosphinat 

Relevant articles and documents

A phosphoryl radical-initiated Atherton-Todd-type reaction under open air

A phosphoryl radical-initiated Atherton-Todd-type reaction using air as the radical initiator and CHCl3 as the halogenating reagent for the phosphorylation of alcohols, phenols, and amines has been developed. This novel transformation provides a highly efficient route to important phosphinates, phosphinic amides, and phosphoramidates in up to 99% yield with a broad substrate scope under very mild conditions (48 examples).

Reactivity of the acids of trivalent phosphorus and their derivatives. Part IX. The > P-O- and > p-s- nucleophiles in the reactions of halophilic substitution

The reaction of the > P-Y- (Y = O; S) nucleophiles with the compounds possessing a C-Br bond and electron-withdrawing groups is described. The isolation of the products derived from dialkyl bromophosphates, the results of the 31P NMR studies, as well as the isolation of bromothiophosphate from the reaction mixture of > P-S- nucleophile and methyl α-bromocarboxylate, are further evidence for halophilic substitution as the principal process in the X-philic substitution/SET tandem mechanism operating in the reaction of these phosphorus nucleophiles with the bromoderivatives possessing electron-withdrawing groups.

Reactions of 7-methoxyimino-4-methylchromene-2,8-dione with phosphines. Preparation of N-substituted 7-amino-8-hydroxy-4-methyl-2H-[1]-benzopyran-2-ones

7-Methoxyimino-4-methylchromene-2,8-dione 2 reacts with triarylphosphines 1(a-d) to give the unexpected 7-arylomino-8-hydroxy-4-methyl-2H-[1]-benzopyran-2-ones 7(a-d) and methyl diarylphosphinates 8(a-d) in high yields. The reaction of 2 with trialkylphosphines 1(e,f) as well as with diphenylphosphine 15 leads to the formation of the N-dialkylphosphinoyl derivatives 11, 12, 14 and the N-diphenylphosphinoyl derivative 19, along with compounds 7(e,f). The methylation of compounds 7a, 7f, 11 and 19 is also studied and reaction mechanisms to explain the formation of the products obtained are suggested.