21800-83-9 Usage
Description
D-Ethylgonendione, also known as Levonorgestrel EP Impurity L, is a light yellow crystalline solid that serves as an intermediate in the synthesis of Norgestrel, a widely used progestin hormone. It plays a crucial role in the pharmaceutical industry due to its chemical properties and its function as a precursor to a vital hormone.
Uses
Used in Pharmaceutical Industry:
D-Ethylgonendione is used as a chemical intermediate for the synthesis of Norgestrel, a progestin hormone. It is essential in the production process of various hormonal medications, including contraceptives and hormone replacement therapies, due to its role in facilitating the synthesis of the active pharmaceutical ingredient.
Used in Contraceptive Applications:
As a precursor to Norgestrel, D-Ethylgonendione indirectly contributes to the development of contraceptive products, such as birth control pills and patches. These contraceptives help in preventing unintended pregnancies by regulating hormonal levels in the body.
Used in Hormone Replacement Therapy:
D-Ethylgonendione, through its role in the synthesis of Norgestrel, is also utilized in hormone replacement therapy (HRT) for conditions like menopause. HRT helps in alleviating symptoms associated with hormonal imbalances and maintaining overall health and well-being in individuals undergoing hormonal changes.
Check Digit Verification of cas no
The CAS Registry Mumber 21800-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,0 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21800-83:
(7*2)+(6*1)+(5*8)+(4*0)+(3*0)+(2*8)+(1*3)=79
79 % 10 = 9
So 21800-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O2/c1-2-19-10-9-15-14-6-4-13(20)11-12(14)3-5-16(15)17(19)7-8-18(19)21/h11,14-17H,2-10H2,1H3/t14-,15+,16+,17-,19-/m0/s1
21800-83-9Relevant articles and documents
Steroid intermediate products and method of their production
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, (2008/06/13)
The invention is directed to novel steroid intermediate products of general formula I STR1 The steroid intermediate products which can be isolated according to the invention are suitable for the synthesis of 13-ethyl-11-methylene-18,19-bisnor-17α-pregn-4-en-20-in-17-ol (desogestrel). Further, processes for producing the steroid intermediate products of general formula I are described. The olefination of the 11-oxo steroids is carried out under the influence of ultrasound.
Synthesis of gon-4-enes
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, (2008/06/13)
1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17α-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.
Tetrahydropyran-2-ols
-
, (2008/06/13)
Stereo-specific total synthesis of steroidal materials. 7-Substituted 3-oxo-1-heptenes or variants thereof are reacted with 2-alkylcycloalkane-1,3-diones yielding 3-substituted 6a β-alkyl-cyclopenta [f] [1] benzopyrans or naphtho [2,1-b] pyrans. These are then subjected to a selective catalytic hydrogenation followed by an introduction of a hydroxy, alkoxy or acyloxy group at the 4a-position to produce a 3-substituted 6a β,4a-hydroxy, alkoxy or acyloxy perhydrocyclopenta [f] [1] benzopyran or perhydro-naphtho [2,1-b] pyran. These latter compounds are then converted into 4- or 5-(3-oxoalkyl)perhydroindene-5-ones or perhydronaphthalene-6-ones which in turn can be converted to known steroidal materials by known methods.
