218162-49-3

Basic information

• Product Name: 2-dimethoxymethyl-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole
• Synonyms: 2-dimethoxymethyl-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole
• CAS NO: 218162-49-3
• Molecular Weight: 360.412
• Mol File: 218162-49-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-dimethoxymethyl-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-dimethoxymethyl-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole(218162-49-3)
• EPA Substance Registry System: 2-dimethoxymethyl-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole(218162-49-3)

Safety Data

• Hazardous Substances Data: 218162-49-3(Hazardous Substances Data)

Upstream product

• 217661-99-9 1-(4-fluorophenyl)-2-(2-methylsulphanylpyrimidin-4-yl)-1-ethanone 
• 403-33-8 methyl 4-flurobenzoate 
• 51673-84-8 dimethoxyacetaldehyde 
• 218162-50-6 2-thiomethylpyrimidin-4-yl-4-fluorophenylbenzil 

Downstream Products

• 218161-94-5 trans-2-(5-methyl-5-carboxymethyl-1,3-dioxan-2-yl)-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole 
• 218161-96-7 cis-2-(5-methyl-5-carboxymethyl-1,3-dioxan-2-yl)-4-(4-fluorophenyl)-5-(2-methylsulfanylpyrimidin-4-yl)-1H-imidazole 
• 218162-34-6 cis-2-(5-methyl-5-carboxymethyl-1,3-dioxan-2-yl)-4-(4-fluorophenyl)-5-(2-methylsulfonylpyrimidin-4-yl)-1H-imidazole 

Relevant articles and documents

An algorithm-directed two-component library synthesized via solid-phase methodology yielding potent and orally bioavailable p38 MAP kinase inhibitors

Previously we reported the identification of RPR200765A, a potent orally bioavailable pyridine - imidazole inhibitor of p38 mitogen-activated protein (MAP) kinase which suppressed paw swelling and joint pathology in streptococcal cell wall-induced arthrit