218301-11-2

Basic information

• Product Name: N-{2'-[(tert-butylamino)sulfonyl]-1,1'-biphenyl-4-yl}-1-(7-isoquinolyl)-3-methyl-1H-pyrazole-5-carboxamide
• Synonyms: N-{2'-[(tert-butylamino)sulfonyl]-1,1'-biphenyl-4-yl}-1-(7-isoquinolyl)-3-methyl-1H-pyrazole-5-carboxamide
• CAS NO: 218301-11-2
• Molecular Weight: 539.658
• Mol File: 218301-11-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-{2'-[(tert-butylamino)sulfonyl]-1,1'-biphenyl-4-yl}-1-(7-isoquinolyl)-3-methyl-1H-pyrazole-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2'-[(tert-butylamino)sulfonyl]-1,1'-biphenyl-4-yl}-1-(7-isoquinolyl)-3-methyl-1H-pyrazole-5-carboxamide(218301-11-2)
• EPA Substance Registry System: N-{2'-[(tert-butylamino)sulfonyl]-1,1'-biphenyl-4-yl}-1-(7-isoquinolyl)-3-methyl-1H-pyrazole-5-carboxamide(218301-11-2)

Safety Data

• Hazardous Substances Data: 218301-11-2(Hazardous Substances Data)

Upstream product

• 23707-37-1 7-aminoisoquinoline 
• 193006-34-7 4-(2'-tert-butylaminosulfonylphenyl)aniline 
• 218301-10-1 ethyl 1-(isoquinolyn-7'-yl)-3-methyl-5-pyrazole carboxylate 

Downstream Products

• 218297-83-7 1-(1'-amino-isoquinol-7'-yl)-3-methyl-5-[(2'-aminosulfonyl-[1,1']-biphen-4-yl)aminocarbonyl]pyrazole 

Relevant articles and documents

NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt forms thereof, wherein rings D-E represent guanidine mimics, which are useful as inhibitors of factor Xa.

Guanidine mimics as factor Xa inhibitors

The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein rings D—E represent guanidine mimics, which are useful as inhibitors of factor Xa.