218780-53-1

Basic information

• Product Name: 1-N-(Methylsulfonyl)-4-piperidinone
• Synonyms: 1-(METHYLSULFONYL)-4-PIPERIDINONE;1-(Methylsulphonyl)-4-piperidinone;1-N-(Methylsulfonyl)-4-piperidinone;1-Methylsulfonyl-4-piperidone;1-(Methylsulphonyl)-4-oxopiperidine;1-Methanesulfonylpiperidin-4-one
• CAS NO: 218780-53-1
• Molecular Formula: C₆H₁₁NO₃S
• Molecular Weight: 177.22
• Mol File: 218780-53-1.mol
• Article Data: 20

Chemical Properties

• Melting Point: 102-103 °C
• Boiling Point: 320.414 °C at 760 mmHg
• Flash Point: 147.581 °C
• Appearance: /
• Density: 1.332 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -6.09±0.20(Predicted)
• CAS DataBase Reference: 1-N-(Methylsulfonyl)-4-piperidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-(Methylsulfonyl)-4-piperidinone(218780-53-1)
• EPA Substance Registry System: 1-N-(Methylsulfonyl)-4-piperidinone(218780-53-1)

Safety Data

• Hazardous Substances Data: 218780-53-1(Hazardous Substances Data)

Usage

General Description

1-N-(Methylsulfonyl)-4-piperidinone is a chemical compound often used in the field of organic chemistry, specifically in the synthesis of various pharmaceuticals due to its versatile nature. This chemical compound belongs to the class of organic compounds known as piperidinones, which are compounds containing a piperidinone ring, a six-membered saturated ring with one nitrogen atom, one ketone group and four carbon atoms. Its sulfur-containing sulfonyl functional group makes it a good leaving group, thus it's frequently used in nucleophilic substitution reactions. It's also important to note that, like all chemicals, improper handling of 1-N-(Methylsulfonyl)-4-piperidinone has associated health risks, hence it should be used in compliance with safety precautions.

InChI:InChI=1/C6H11NO3S/c1-11(9,10)7-4-2-6(8)3-5-7/h2-5H2,1H3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 59039-18-8 8-methanesulfonyl-1,4-dioxa-8-aza-spiro[4.5]decane 
• 41979-39-9 4-piperidone hydrochloride 
• 40064-34-4 4-piperidone monohydrochloride monohydrate 
• 7143-01-3 Methanesulfonic anhydride 
• 40064-34-4 piperidine-4,4-diol hydrochloride 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 1155995-63-3 C₁₃H₂₀N₂O₂S 
• 438585-61-6 N-methyl‐1‐(methylsulphonyl)piperidin‐4‐amine 
• 1190979-74-8 2-chloro-4-(1-(methylsulfonyl)piperidin-4-ylamino)phenol 
• 802536-13-6 N,1-dimethyl-8-([1-(methylsulfonyl)piperidin-4-yl]amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide 
• 1264755-13-6 1-methanesulfonyl-3-(4-trifluoromethyl-benzoyl)-piperidin-4-one 
• 400797-90-2 5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine 
• 400801-26-5 5-methanesulfonyl-1-((R)-oxiranylmethyl)-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine 
• 400797-45-7 (S)-5-Dimethylamino-3-(1-{2-hydroxy-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperidin-4-yl)-1-methyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one 
• 1264755-18-1 5-dimethylamino-3-(1-{2-(S)-hydroxy-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperidin-4-yl)-1-methyl-1,3-dihydro-imidazo[4,5-b]pyridin-2-one hydrochloride 
• 1264755-22-7 1-chloro-3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propan-2(R)-ol 
• 1613304-95-2 N-isobutyl-4-(1-methanesulfonylpiperidin-4-ylidenemethyl)benzenesulfonamide 
• 1630952-69-0 8-(1'-(methylsulfonyl)spiro[chroman-2,4'-piperidin]-4-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 
• 1048034-83-8 2-chloro-5-(5-methanesulfonyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-benzonitrile 

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