21900-33-4

Basic information

• Product Name: 3-BROMO-4-METHYL-BENZOYL CHLORIDE
• Synonyms: 3-BROMO-4-METHYL-BENZOYL CHLORIDE
• CAS NO: 21900-33-4
• Molecular Formula: C₈H₆BrClO
• Molecular Weight: 233.49
• Mol File: 21900-33-4.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 281.9 °C at 760 mmHg
• Flash Point: 124.3 °C
• Appearance: /
• Density: 1.574 g/cm³
• CAS DataBase Reference: 3-BROMO-4-METHYL-BENZOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-METHYL-BENZOYL CHLORIDE(21900-33-4)
• EPA Substance Registry System: 3-BROMO-4-METHYL-BENZOYL CHLORIDE(21900-33-4)

Safety Data

• Hazardous Substances Data: 21900-33-4(Hazardous Substances Data)

Usage

Description

3-Bromo-4-methyl-benzoyl chloride, with the chemical formula C8H6BrClO, is an organic compound that falls under the category of benzoyl chlorides. It is a colorless to pale yellow liquid with a pungent odor and is highly reactive, making it a valuable intermediate in various chemical syntheses.

Uses

Used in Pharmaceutical Industry:
3-Bromo-4-methyl-benzoyl chloride is used as a key intermediate in the synthesis of pharmaceuticals. Its reactivity allows it to form bonds with other molecules, facilitating the creation of new drug compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-4-methyl-benzoyl chloride serves as an essential intermediate for the production of various agrochemicals. Its ability to react with other molecules contributes to the development of new compounds for agricultural applications.
Used in Organic Synthesis:
3-Bromo-4-methyl-benzoyl chloride is utilized as a versatile intermediate in organic synthesis for creating a range of organic compounds. Its high reactivity makes it suitable for forming bonds and constructing complex molecular structures.
It is crucial to handle 3-Bromo-4-methyl-benzoyl chloride with care due to its corrosive nature, which can cause skin and eye irritation upon contact. Proper safety measures should be taken to minimize risks during its use in various applications.

Upstream product

• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 7697-28-1 4-bromo-3-methylbenzoic acid 
• 104901-43-1 methyl 3-bromo-4-methylbenzoate 

Downstream Products

• 292863-15-1 N,N-diethyl 3-bromo-4-methylbenzamide 
• 309928-70-9 3-bromo-4-methyl-benzoic acid anthracen-9-ylmethyl ester 
• 957228-80-7 (3-bromo-4-methylphenyl)(4-ethoxyphenyl)methanone 
• 628711-76-2 N-((1R)-1-phenylethyl)(3-bromo-4-methylphenyl)carboxamide 
• 856252-70-5 3 -bromo-N-cyclopropyl-4-methylbenzamide 
• 183723-09-3 3-bromo-4-methyl-benzamide 
• 1132825-32-1 3-bromo-4-methyl-N-(4-(morpholin-4-yl)phenyl)benzamide 
• 1154427-35-6 3-bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4-methylbenzamide 
• 1154427-37-8 2-(3-bromo-4-methylphenyl)-4,4-dimethyl-4,5-dihydrooxazole 
• 1177558-32-5 (3-bromo-4-methylphenyl)methanamine 
• 1211578-89-0 2-(3-bromo-4-methyl-phenyl)-oxazole 
• 1509789-19-8 C₁₁H₁₂BrNO₃ 
• 838596-29-5 3-[2-(sec-butylcarbamoyl)phenylcarbamoyl]-6-methyl-N-(2,5-dimethylphenyl)benzenesulfonamide 
• 1628027-29-1 C₁₉H₂₁ClN₂O₄S 

Relevant articles and documents

Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

RAS oncogenes have been implicated in >30% of human cancers, all representing high unmet medical need. The exquisite dependency on CRAF kinase in KRAS mutant tumors has been established in genetically engineered mouse models and human tumor cells. To date

RECEPTOR TYROSINE KINASE INHIBITORS FOR TREATMENT OF PROTEIN KINASE MODULATION-RESPONSIVE DISEASE OR DISORDER

Ephrin type receptor tyrosine kinase inhibitors, also known as Eph tyrosine kinase receptor inhibitors, for treating cancer, an inflammatory disease, an autoimmune disease, or a degenerative disease characterized at least in part by the abnormal activity

Macrofilaricidal Benzimidazole-Benzoxaborole Hybrids as an Approach to the Treatment of River Blindness: Part 2. Ketone Linked Analogs

The optimization of a series of benzimidazole-benzoxaborole hybrid molecules linked via a ketone that exhibit good activity against Onchocerca volvulus, a filarial nematode responsible for the disease onchocerciasis, also known as river blindness, is desc