21929-66-8

Basic information

• Product Name: Z-HIS(BZL)-OH
• Synonyms: Z-N-IM-BENZYL-L-HISTIDINE;Z-HIS(BZL)-OH;Z-HISTIDINE(BZL)-OH;N-CARBOBENZOXY-IM-BENZYL-L-HISTIDINE;NALPHA-CBZ-N-IM-BENZYL-L-HISTIDINE;N-ALPHA-CARBOBENZOXY-N-IM-BENZYL-L-HISTIDINE;N-Benzyloxycarbonyl-im-benzyl-L-histidine;Cbz-His(Bzl)-OH
• CAS NO: 21929-66-8
• Molecular Formula: C₂₁H₂₁N₃O₄
• Molecular Weight: 379.41
• Product Categories: Cbz-Amino acid series
• Mol File: 21929-66-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 649.3°Cat760mmHg
• Flash Point: 346.5°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 9.61E-18mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: −20°C
• BRN: 55593
• CAS DataBase Reference: Z-HIS(BZL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-HIS(BZL)-OH(21929-66-8)
• EPA Substance Registry System: Z-HIS(BZL)-OH(21929-66-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 21929-66-8(Hazardous Substances Data)

Usage

General Description

Z-HIS(BZL)-OH, also known as Benzyloxycarbonyl-L-histidine, is a chemical compound used mainly for research purposes. It belongs to the family of amino acids and peptides which are fundamental components of cells that carry out critical functions in the body. This chemical has a molecular formula C14H14N4O4. As a specifically labelled compound, it is typically derived from L-Histidine and is utilised in the production of a variety of pharmaceuticals and medicinal research processes due to its important biological activity. Being a protective group, the benzyloxycarbonyl group (Bzl or Z), helps in increasing the effectiveness and optimisation of the synthesised drugs. However, extensive caution has to be observed while handling this compound due to its potential hazards and reactivity.

InChI:InChI=1/C21H21N3O4/c25-20(26)19(23-21(27)28-14-17-9-5-2-6-10-17)11-18-13-24(15-22-18)12-16-7-3-1-4-8-16/h1-10,13,15,19H,11-12,14H2,(H,23,27)(H,25,26)

Upstream product

• 16832-24-9 1-benzyl-L-histidine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1059596-74-5 N-Cbz-N'-benzyl-L-histidine p-tolylthiol ester 
• 26582-89-8 N^α-carbobenzoxy-N^im-benzyl-L-histidine hydrazide 
• 95485-23-7 N^α-carbobenzoxy-N^im-benzyl-L-histidyl-L-valine methyl ester 
• 122766-72-7 1-benzyl-N^α-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-L-histidine-benzyl ester 
• 95433-50-4 N-(carbobenzyloxy)-im-benzylhistidine cyanomethyl ester 
• 66438-51-5 N^α-carbobenzoxy-N^im-benzyl-L-histidine pentachlorophenyl ester 
• 95485-20-4 N^α-carbobenzoxy-N^im-benzyl-L-histidine methyl ester hydrochloride 
• 30891-94-2 benzyl-N-carboxy-L-histidine anhydride 
• 108722-10-7 1-benzyl-N^α-benzyloxycarbonyl-L-histidyl=>L-valyl=>L-tyrosine-methyl ester 
• 120548-57-4 N-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-glycine-benzyl ester 
• 105374-43-4 N-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-glycine