219754-02-6 Usage
General Description
Boceprevir intermediate, also known as N-[(1R,2S)-2-(4-chlorophenyl)cyclopropyl]-3-phenylpropanamide, is a chemical compound that serves as a key intermediate in the production of the antiviral medication boceprevir. Boceprevir is a protease inhibitor used in the treatment of chronic hepatitis C virus (HCV) infection. The intermediate compound is crucial for the synthesis of boceprevir and is an important building block in the manufacturing process. It undergoes several chemical reactions and modifications to ultimately form boceprevir, which inhibits the replication of the HCV virus and helps to improve liver function in HCV-infected individuals. The production and availability of boceprevir intermediate are essential for the production of the medication and for addressing the global burden of HCV infection.
Check Digit Verification of cas no
The CAS Registry Mumber 219754-02-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,7,5 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 219754-02:
(8*2)+(7*1)+(6*9)+(5*7)+(4*5)+(3*4)+(2*0)+(1*2)=146
146 % 10 = 6
So 219754-02-6 is a valid CAS Registry Number.
219754-02-6Relevant articles and documents
ANTIVIRAL COMPOUNDS FOR THE TREATMENT OF CORONAVIRUS, PICORNAVIRUS AND NOROVIRUS INFECTIONS
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Paragraph 0206, (2021/12/31)
Provided herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, pharmaceutical compositions that include a compound described herein (including pharmaceutically acceptable salts of a compound described herein) and methods of synthesizing the same. Also provided herein are methods of treating coronavirus, Picomavirus and Norovims infections with a compound of Formula (I), or a pharmaceutically acceptable salt thereof.
HCV PROTEASE INHIBITORS AND USES THEREOF
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Page/Page column 51, (2010/03/04)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Design, synthesis and evaluation of poly-L-proline type-II peptide mimics based on the 3-azabicyclo[3.1.0]hexane system
Zhang, Rui,Madalengoitia, Jose S.
, p. 330 - 331 (2007/10/03)
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