22006-43-5

Basic information

• Product Name: Benzene, pentafluoro(fluoromethyl)-
• CAS NO: 22006-43-5
• Molecular Formula: C7H2F6
• Molecular Weight: 200.083
• Mol File: 22006-43-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, pentafluoro(fluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, pentafluoro(fluoromethyl)-(22006-43-5)
• EPA Substance Registry System: Benzene, pentafluoro(fluoromethyl)-(22006-43-5)

Safety Data

• Hazardous Substances Data: 22006-43-5(Hazardous Substances Data)

Upstream product

• 19161-27-4 pentafluorobenzaldehyde hydrazone 
• 653-37-2 perfluorobenzaldehyde 
• 440-60-8 (2,3,4,5,6-pentafluorophenyl)methanol 
• 108-88-3 toluene 
• 771-56-2 2,3,4,5,6-pentafluorotoluene 
• 1765-40-8 (bromomethyl)pentafluorobenzene 

Downstream Products

• 1081978-38-2 C₇H₄F₅N 
• 10534-43-7 1-(difluoromethyl)nonafluorocyclohex-1-ene 
• 111180-52-0 1-fluoromethylnonafluorocyclohexene 
• 111180-51-9 1-fluoromethylheptafluoro-1,4-cyclohexadiene 
• 111180-53-1 1-difluoromethylheptafluoro-1,4-cyclohexadiene 
• 22006-44-6 difluoromethylpentafluorobenzene 

Relevant articles and documents

FLUORINATIONS WITH COMPLEX METAL FLUORIDES. PART 9. FLUORINATIONS OF TOLUENE AND XYLENE DERIVATIVES BY MEANS OF CAESIUM TETRAFLUOROCOBALTATE(III)

Benzotrifluoride at 320 deg C afforded some m-fluorobenzotrifluoride and octafluorotoluene (III), together with perfluoromethylcyclohexane (I), and also traces of 2H-heptafluorotoluene and 1-trifluoromethylnonafluorocyclohex-1-ene.Toluene itself gave (difluoromethyl)benzene, fluoro- and difluoro-methylpentafluorobenzene, difluoromethylundecafluorocyclohexane and (I); also traces of di- and tri-fluoromethylnonafluorocyclohex-1-ene: no benzotrifluoride or (III) were detected. 1,3-Bis(trifluoromethyl)benzene at 420 deg C gave 4,5,6-trifluoro-1,3-bis(trifluoromethyl)benzene, decafluoro-1,3-dimethylbenzene, and perfluoro-1,3-dimethylcyclohexane.Para-xylene at 350 deg C afforded 1,4-bis(difluoromethyl)tetrafluorobenzene, 1-difluoromethyl-4-trifluoromethyltetrafluorobenzene, decafluoro-1,4-dimethylbenzene (XIX), and perfluoro-1,4-dimethylcyclohexane (XVIII).Defluorination occurred to a significant extent on passage of the saturated cyclic fluorocarbons (I) and (XVIII) over the fully spent fluorinating agent (presumably caesium trifluorocobaltate) at ca. 400 deg C; the fluorocarbon arenes, (III) and (XIX) respectively, were obtained.

Denitrogenative hydrofluorination of aromatic aldehyde hydrazones using (difluoroiodo)toluene

An operationally simple conversion of aromatic aldehyde hydrazones to monofluoromethylated arenes is reported. The hypervalent iodine reagent TolIF2 serves as an oxidant, converting the hydrazone to the corresponding diazo compounds. The by-product of the oxidation process, HF, is consumed in situ by a denitrogenative hydrofluorination reaction of the diazo group.

Pesticidal fluorinated esters of the pyrethrin or pyrethroid type

The invention concerns novel pesticidal esters of the pyrethrin or pyrethroid type in which the methylene group bonded to the ester carbonyl and/or ester oxygen bears a fluorine substituent. The compounds of the invention are active against insect pests including flies, moths, aphids and beetles and acarina pests including ticks.