220106-55-8Relevant articles and documents
A short synthesis of α-herbertenol featuring the use of a dihydropyranone as a 1,5-diketone synthon
Harrowven, David C.,Hannam, Joanne C.
, p. 9573 - 9574 (1998)
The paper describes a short synthesis of α-herbertenol. Key features are the addition of dihyropyranone 5 to an aryllithium to give 1,5-diketone 7; a titanium(O) mediated cyclisation of 7 to diol 8 and a sequential methylation of 8 to herbertenol methyl ether 9.