220677-63-4

Basic information

• Product Name: ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate
• Synonyms: ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate
• CAS NO: 220677-63-4
• Molecular Weight: 363.243
• Mol File: 220677-63-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate(220677-63-4)
• EPA Substance Registry System: ethyl N-(3,4-dichlorobenzyl)-4-aminoindole-2-carboxylate(220677-63-4)

Safety Data

• Hazardous Substances Data: 220677-63-4(Hazardous Substances Data)

Upstream product

• 220677-29-2 Ethyl N-(3,4-dichlorobenzyl)-4-nitroindole-2-carboxylate 
• 102-47-6 3,4-Dichlorophenylmethyl chloride 
• 33858-35-4 ethyl 4-amino-1H-indole-2-carboxylate 

Downstream Products

• 288067-67-4 ethyl 4-chloroacetamido-N-(3,4-dichlorobenzyl)indole-2-carboxylate 
• 287482-04-6 N-(3,4-dichlorobenzyl)-2-ethoxycarbonylindole-4-diazonium tetrafluoroborate 

Relevant articles and documents

N-Benzylindole-2-carboxylic acids: Potent functional antagonists of the CCR2b chemokine receptor

Screening of the corporate database led to the discovery of a novel series of N-benzylindole-2-carboxylic acid CCR2b chemokine receptor antagonists. These compounds demonstrate high affinity and functional inhibition of the CCR2b receptor. A discussion of

Monocyte chemoattractant protein-1 inhibitor compounds

The invention concerns the use of a compound of the formula (I) in which Z, X, T, A, R1, R2, p and q have any of the meanings defined herein, and their pharmaceutically acceptable salts or in vivo hydrolysable esters, in the treatment of a disease or condition mediated by monocyte chemoattractant protein-1 (MCP-1). Certain of the components of formula (I) are novel and are provided, together with pharmaceutical compositions thereof, as further features of the invention.