220741-33-3

Basic information

• Product Name: 4-(4-benzyloxy-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(4-benzyloxy-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 220741-33-3
• Molecular Weight: 382.503
• Mol File: 220741-33-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-(4-benzyloxy-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-benzyloxy-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester(220741-33-3)
• EPA Substance Registry System: 4-(4-benzyloxy-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester(220741-33-3)

Safety Data

• Hazardous Substances Data: 220741-33-3(Hazardous Substances Data)

Upstream product

• 6373-46-2 p-benzyloxyaniline 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 51388-20-6 4-benzyloxyaniline hydrochloride 
• 71072-37-2 1-tert-butyl-carbonyl-4-piperidone 

Downstream Products

• 220741-66-2 4-[(4-benzyloxy-phenyl)-(3-methyl-butyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester 
• 220741-34-4 4-(4-benzyloxy-phenylamino)-piperidine 
• 241499-29-6 4-[(4-benzyloxy-phenyl)-(3-methyl-but-2-enyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester 
• 247116-65-0 Azepane-1-carboxylic acid ((S)-1-{4-[(4-benzyloxy-phenyl)-(3-methyl-butyl)-amino]-piperidine-1-carbonyl}-3-methyl-butyl)-amide 
• 220741-67-3 (4-benzyloxy-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine 

Relevant articles and documents

TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY

Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, Q2, L1 and n are as defined herein. The compounds have antifungal properties and are useful in the treatment of fungal infections, including infections that are resistant to conventions anti-fungal agents. Q1 is selected from: (Formulae Ia, Ib, Ic, Id, Ie, If, Ig, Ih, Ii, Ij and Ik) wherein * indicates the point of attachment to L1.

Heterocyclic substituted aniline calcium channel blockers

The present invention provides compounds that block calcium channels having the Formula I shown below. STR1The present invention also provides methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, epilepsy, asthma, amyotrophic lateral sclerosis, or pain and to pharmaceutical compositions that contain the compounds of Formula I.

Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties

In this article, the rationale for the design, synthesis, and biological evaluation of a series of N-type voltage-sensitive calcium channel (VSCC) blockers is described. N-Type VSCC blockers, such as ziconotide, have shown utility in several models of str