220875-88-7

Basic information

• Product Name: 4-(chloromethyl)-N-methylbenzamide
• Synonyms: 4-(chloromethyl)-N-methylbenzamide;4-(chloromethyl)-N-methylbenzamide(SALTDATA: FREE)
• CAS NO: 220875-88-7
• Molecular Formula: C₉H₁₀ClNO
• Molecular Weight: 183.6348
• Mol File: 220875-88-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 346.917°C at 760 mmHg
• Flash Point: 163.61°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 4-(chloromethyl)-N-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(chloromethyl)-N-methylbenzamide(220875-88-7)
• EPA Substance Registry System: 4-(chloromethyl)-N-methylbenzamide(220875-88-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 220875-88-7(Hazardous Substances Data)

Usage

General Description

4-(chloromethyl)-N-methylbenzamide is a chemical compound with the molecular formula C9H10ClNO. It is a benzamide derivative with a chloromethyl group and a methyl group attached to the nitrogen atom. 4-(chloromethyl)-N-methylbenzamide is used in research and chemical synthesis, and its properties and uses are still being studied. 4-(chloromethyl)-N-methylbenzamide may have potential applications in pharmaceuticals, agrochemicals, and other industrial uses, although further research is needed to determine its full potential and safety profile.

InChI:InChI=1/C9H10ClNO/c1-11-9(12)8-4-2-7(6-10)3-5-8/h2-5H,6H2,1H3,(H,11,12)

Upstream product

• 876-08-4 p-(chloromethyl)benzoyl chloride 
• 74-89-5 methylamine 
• 1642-81-5 p-(chloromethyl)benzoic acid 
• 99-94-5 p-Toluic acid 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 220875-89-8 4-(1-methyltetrazol-5-yl)benzyl chloride 
• 1610612-03-7 N-methyl-4-((trimethylstannyl)methyl)benzamide 

Relevant articles and documents

The Pd-catalyzed synthesis of difluoroethyl and difluorovinyl compounds with a chlorodifluoroethyl iodonium salt (CDFI)

Herein, we report a simple and efficient method for the direct installation of chlorodifluoroethyl group onto aromatic molecules of various aromatic amides with a new 2-chloro,2,2-difluoroethyl(mesityl)iodonium salt (CDFI). Moreover, the chlorodifluoroeth

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES

The present invention provides compounds of formula I: [INSERT FORMULA HERE] or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.

N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.

A systematic structure-activity relationship investigation of the lead compound 1 resulted the identification of several N-[(substituted alkyl)cycloalkanoyl]-4-[((2,6-dichlorophenyl)carbonyl)amino]-L-phenylalanine derivatives as potent VCAM/VLA-4 antagonists. The data are consistent with a model of these compounds in which these alkanoylphenylalanines reside in a compact gauche (-) bioactive conformation.