220950-35-6

Basic information

• Product Name: 4-(3-Hydroxyphenyl)benzoic acid
• Synonyms: 4-(3-Hydroxyphenyl)benzoic acid
• CAS NO: 220950-35-6
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.22
• Mol File: 220950-35-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 4-(3-Hydroxyphenyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-Hydroxyphenyl)benzoic acid(220950-35-6)
• EPA Substance Registry System: 4-(3-Hydroxyphenyl)benzoic acid(220950-35-6)

Safety Data

• Hazardous Substances Data: 220950-35-6(Hazardous Substances Data)

Usage

General Description

4-(3-Hydroxyphenyl)benzoic acid is a chemical compound with the molecular formula C13H10O3. It is a derivative of benzoic acid and contains a hydroxyphenyl group. This chemical is commonly used as a building block in the synthesis of pharmaceuticals, dyes, and polymers. It has potential applications in the field of medicinal chemistry due to its ability to interact with biological targets. Additionally, it is a versatile intermediate for the production of various organic compounds. Its properties and structure make it an important component for the development of new materials and compounds in the chemical industry.

Upstream product

• 591-20-8 3-Bromophenol 
• 14047-29-1 4-carboxyphenylboronic acid 
• 81443-43-8 methyl 3'-Methoxy(1,1'-biphenyl)-4-carboxylate 
• 92-92-2 biphenyl-4-carboxylic acid 
• 619-58-9 4-iodobenzoic acid 
• 87199-16-4 3-Formylphenylboronic acid 
• 222180-23-6 3’-formyl-[1,1’-biphenyl]-4-carboxylic acid 

Downstream Products

• 579511-01-6 methyl 3'-hydroxy-[1,1'-biphenyl]-4-carboxylate 
• 1354553-12-0 3'-hydroxy-biphenyl-4-carboxylic acid 3-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ylcarbamoyl)-benzylamide 

Relevant articles and documents

Selectivity in the photo-Fenton and photocatalytic hydroxylation of biphenyl-4-carboxylic acid and derivatives (viz. 4-phenylsalicylic acid and 5-phenylsalicylic acid)

The selectivity of hydroxylation of the distal rings of 4-phenylbenzoic acid, 4-phenylsalicylic acid, and 5-phenylsalicylic acid were determined using partial TiO2-mediated photocatalytic degradation and photo-Fenton conditions. This separation of the binding site from the phenyl group being hydroxylated allows a less-biased evaluation. The hydroxylation regiochemistry behaves as qualitatively expected for an electrophilic reaction, given the assumption that 4-carboxyphenyl is a slightly electron-withdrawing substituent. Selectivity for hydroxylation of the distal phenyl in 4- and 5-phenylsalicylic acid is reversed, due to the reversal of the electronic demand, while adsorption to the TiO2 surface is assumed to be analogous for the two structures. Copyright

Amidocarboxylic acid derivatives

Amidocarboxylic acid derivatives of the formula: wherein R1 represents a hydrogen atom, etc.; R2 represents an alkylene group; R3 represents a hydrogen atom, etc.; R4 represents a hydrogen atom, etc.; X represents a substituted or unsubstituted aryl group, etc.,; Y represents an oxygen atom, etc.; Z represents an alkylene group, etc.; and W represents an alkyl group, etc.; and pharmacologically acceptable salts thereof and pharmacologically acceptable esters thereof are useful as the active ingredient of pharmaceutical compositions. They may be used to treat specified diseases, including diabetes mellitus, hyperlipemia, arteriosclerosis, hypertension, etc.