221187-50-4 Usage
Description
2'-(DICYCLOHEXYLPHOSPHINO)ACETOPHENONE & is an organic compound that acts as a cocatalyst in various chemical reactions. It is characterized by the presence of a dicyclohexylphosphino group attached to an acetophenone moiety, which contributes to its unique catalytic properties.
Uses
Used in Palladium-catalyzed amination reactions:
2'-(DICYCLOHEXYLPHOSPHINO)ACETOPHENONE & is used as a cocatalyst for palladium-catalyzed amination reactions. Its dicyclohexylphosphino group enhances the catalytic activity of palladium, facilitating the formation of carbon-nitrogen bonds in various organic substrates.
Used in Palladium/P,O-Ligand-catalyzed Suzuki cross-coupling:
2'-(DICYCLOHEXYLPHOSPHINO)ACETOPHENONE & is also employed as a cocatalyst in palladium/P,O-ligand-catalyzed Suzuki cross-coupling reactions. Its presence improves the efficiency and selectivity of the reaction, enabling the formation of carbon-carbon bonds between aryl and vinyl halides with boronic acids or esters.
Check Digit Verification of cas no
The CAS Registry Mumber 221187-50-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,8 and 7 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 221187-50:
(8*2)+(7*2)+(6*1)+(5*1)+(4*8)+(3*7)+(2*5)+(1*0)=104
104 % 10 = 4
So 221187-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H33O2P/c1-22(23-16-17-24-22)20-14-8-9-15-21(20)25(18-10-4-2-5-11-18)19-12-6-3-7-13-19/h8-9,14-15,18-19H,2-7,10-13,16-17H2,1H3
221187-50-4Relevant articles and documents
Catalyst ligands, catalyst compositions, catalyst metal complexes and processes for cross-coupling aromatic boron compounds with aromatic halogens or perfluoroalkylsulfonates
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, (2008/06/13)
The present invention discloses new organic compounds (e.g., ligands), their metal complexes and compositions using those compounds. The invention also relates to the field of catalysis. In particular, this invention relates to new compounds which when combined with suitable metals or metal precursor compounds provide useful catalysts for various bond-forming reactions, including Suzuki cross-coupling reactions. The invention also relates to performing Suzuki cross coupling reactions with unreactive aryl-chlorides.