221279-14-7Relevant articles and documents
Design, synthesis and biological evaluation of novel substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors
Xu, Wen-Ting,Jin, Ning,Xu, Jing,Xu, Yun-Gen,Wang, Qiu-Juan,You, Qi-Dong
scheme or table, p. 3283 - 3287 (2010/03/31)
A novel series of substituted benzoylguanidine derivatives were designed and synthesized as potent NHE1 inhibitors. Most compounds can significantly inhibit NHE1-mediated platelet swelling in a concentration-dependent manner, among which compound 5f (ICs