221385-25-7

Basic information

• Product Name: 1-(2,4-dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide
• Synonyms: 1-(2,4-dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide
• CAS NO: 221385-25-7
• Molecular Weight: 474.346
• Mol File: 221385-25-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,4-dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide(221385-25-7)
• EPA Substance Registry System: 1-(2,4-dichloro-phenyl)-4-methyl-5-(4-nitro-phenyl)-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide(221385-25-7)

Safety Data

• Hazardous Substances Data: 221385-25-7(Hazardous Substances Data)

Upstream product

• 5446-18-4 2,4-dichlorophenyl hydrazine hydrochloride 
• 2213-43-6 1-Aminopiperidine 
• 221385-23-5 1-(2,4-dichlorophenyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 93-55-0 1-phenyl-propan-1-one 

Downstream Products

• 183232-66-8 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide 
• 221385-28-0 5-(4-amino-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide 

Relevant articles and documents

Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists

As a potent, specific antagonist for the brain cannabinoid receptor (CB1), the biarylpyrazole N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A; 1) was the lead compound for initiating studies desi