221910-19-6

Basic information

• Product Name: 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE
• Synonyms: 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE;2-((4-Chlorophenyl)ethynyl)aniline
• CAS NO: 221910-19-6
• Molecular Formula: C₁₄H₁₀ClN
• Molecular Weight: 227.6889
• Mol File: 221910-19-6.mol
• Article Data: 39

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE(221910-19-6)
• EPA Substance Registry System: 2-(4-CHLORO-PHENYLETHYNYL)-PHENYLAMINE(221910-19-6)

Safety Data

• Hazardous Substances Data: 221910-19-6(Hazardous Substances Data)

Usage

General Description

2-(4-Chloro-phenylethynyl)-phenylamine is a chemical compound that belongs to the category of phenylamine derivatives. It is a combination of a phenylamine group and a chloro-phenylethynyl group, and is typically used in research settings as a building block for the synthesis of various organic compounds. Its chemical structure and properties make it suitable for a range of applications including pharmaceuticals, agrochemicals, and electronic materials. It may also be used as a precursor in the development of new drugs, dyes, and other functional materials due to its potential reactivity and versatility in organic synthesis.

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 201230-82-2 carbon monoxide 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 52670-38-9 2-ethynylaniline 
• 108-91-8 cyclohexylamine 
• 615-43-0 2-iodophenylamine 
• 873-73-4 4-n-chlorophenylacetylene 
• 768-60-5 4-methoxyphenylacetylen 
• 104-88-1 4-chlorobenzaldehyde 
• 77295-59-1 1-chloro-4-(2,2-dibromovinyl)benzene 
• 62-53-3 aniline 
• 95-53-4 o-toluidine 

Downstream Products

• 1211-35-4 2-(4-chlorophenyl)-1H-indole 
• 1103523-12-1 C₂₂H₂₀ClNO₂ 
• 1220451-86-4 C₂₀H₁₈ClNO₂ 
• 1201632-52-1 C₁₅H₁₁ClN₂O 
• 1329007-21-7 11-(4-chlorophenyl)-6-phenyl-11H-indeno[1,2-c]quinolin-11-ol 
• 1353883-57-4 C₁₆H₈Cl₂F₃N 
• 1353882-74-2 N-benzyl-N'-(2-((4-chlorophenyl)ethynyl)phenyl)-2,2,2-trifluoroacetimidamide 
• 1353883-03-0 (Z)-N-(1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2,2-trifluoroethylidene)-1-phenylmethanamine 
• 1351667-33-8 C₁₅H₁₂ClNO₂S 
• 1354644-49-7 2-(4-chlorophenyl)-5-{2-(4-chlorophenyl)-1H-indol-1-yl}-1,3,4-oxadiazole 
• 1361452-26-7 11-allyl-11-(4-chlorophenyl)-6-phenyl-11H-indeno[1,2-c]quinoline 
• 1361452-42-7 11-chloro-11-(4-chlorophenyl)-6-phenyl-11H-indeno[1,2-c]quinoline 
• 1373169-81-3 ethyl 4-(4-chlorobenzoyl)-2-phenylquinoline-3-carboxylate 
• 1374309-65-5 C₂₅H₂₀ClNO₂ 

Relevant articles and documents

Palladium-assisted multicomponent synthesis of 2-aryl-4-aminoquinolines and 2-aryl-4-amino[1,8]naphthyridines

A palladium-mediated multicomponent domino reaction leading to 2-aryl-4-amino-quinolines and 2-aryl-4-amino[1,8]naphthyridines is reported. The scope of the reaction was examined using carbon monoxide, two 2-ethynyl-arylamines, four aryl iodides, and 10 primary amines as substrates. The selection of the appropriate catalytic system was achieved testing several palladium/phosphine systems and overrides previously reported drawbacks associated with the use of primary amines in related reactions. Moreover several features concerning the role of both palladium [(0) and (II)] and phosphines are reported.

Copper-Catalyzed Enantioselective C-H Arylation between 2-Arylindoles and Hypervalent Iodine Reagents

The copper-catalyzed enantioselective C-H arylation between 2-arylindoles and hypervalent iodine reagents has been successfully developed, which provides a convenient and economical route to the highly atroposelective synthesis of axially chiral indole de

Copper(I)-Mediated Cascade Annulation via Dual C-H/C-H Activation: Access to Benzo[a]carbazolic AEEgens

A Cu(I)-mediated cascade cyclization/annulation of unprotectedo-alkynylanilines with maleimides in one pot is developed. The protocol offers sequential formation of one C-N and two C-C bonds to deliver fused benzo[a]carbazoles having free NH skeletons. The annulated products display fluorescence emission in the range of 485-502 nm with a large Stokes shift and fluorescence lifetime of ～17 ns. The annulated3aadisplays AEE behavior in the ethanol/hexane system and possesses marigold-flower-like morphology at the aggregated state. Cell viability assays enumerate biocompatible AEEgens, while their high intracellular fluorescence depicts cell imaging applicability.