22282-60-6 Usage
General Description
Pyridine, 2-iodo-4-methyl-, also known as 4-Methyl-2-iodopyridine, is a chemical compound with the molecular formula C6H6INO. This light-yellow solid substance is commonly used in the practice of medicinal chemistry and organometallic chemistry. It is a critical intermediate used in the synthesis of various pharmaceutical compounds. Like most organoiodides, it is a potentially hazardous compound and should be handled with caution as it may cause skin and eye irritation, and may be harmful if inhaled or swallowed.
Check Digit Verification of cas no
The CAS Registry Mumber 22282-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,8 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22282-60:
(7*2)+(6*2)+(5*2)+(4*8)+(3*2)+(2*6)+(1*0)=86
86 % 10 = 6
So 22282-60-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H6IN/c1-5-2-3-8-6(7)4-5/h2-4H,1H3
22282-60-6Relevant articles and documents
Cheap and easy synthesis of highly functionalized (het)aryl iodides via the aromatic finkelstein reaction
Meyer-Eppler, Georg,Kuechler, Lea,Tenten, Christina,Benkhaeuser, Christian,Brueck, Stefanie,Luetzen, Arne
, p. 1085 - 1090 (2014/05/06)
Aryl iodides are superior coupling partners in cross-couplingA- reactions compared to the corresponding chlorides or bromides. Unfortunately, the iodides are much more expensive, if commercially available at all, than the other halides. Thus, it is often mandatory to transform the available bromides into the corresponding iodides. The copper-catalyzed aromatic Finkelstein reaction turned out to be the method of choice to prepare a number of highly functionalized iodo(het)aryls, including pyridines, 2,2′-bipyridines, and chiral compounds. Georg Thieme Verlag Stuttgart? New York.
