222967-31-9

Basic information

• Product Name: (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester
• Synonyms: (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester
• CAS NO: 222967-31-9
• Molecular Weight: 500.502
• Mol File: 222967-31-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester(222967-31-9)
• EPA Substance Registry System: (1R,2R,4S,5S,6R,7S)-1,5-Bis-benzyloxymethyl-6,7-dihydroxy-3,8-dioxa-tricyclo[3.2.1.0^2,4]octane-6,7-dicarboxylic acid dimethyl ester(222967-31-9)

Safety Data

• Hazardous Substances Data: 222967-31-9(Hazardous Substances Data)

Upstream product

• 1883-75-6 2,5-bis-(hydroxymethyl)furan 
• 222967-29-5 (1S,4R)-1,4-Bis-benzyloxymethyl-7-oxa-bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester 
• 222967-30-8 (1R,2R,4S,5S)-1,5-Bis-benzyloxymethyl-3,8-dioxa-tricyclo[3.2.1.0^2,4]oct-6-ene-6,7-dicarboxylic acid dimethyl ester 
• 174153-23-2 2,5-Bis-benzyloxymethyl-furan 
• 100-39-0 benzyl bromide 

Relevant articles and documents

A new synthetic route for construction of the core of Zaragozic acids

A new synthetic route for construction of the core moiety of zaragozic acids from 2,5-furandimethanol (2) is described. This synthesis involves highly stereocontrolled transformation of 2 into 7-oxabicyclo[2.2.1]heptane derivative 13, and the Grob fragmentation-reduction-iodo acetalization reaction (one-pot process) of 13 as a key step to give 16.