22313-70-8

Basic information

• Product Name: Thiourea, N,N'-bis[(4-methoxyphenyl)methyl]-
• CAS NO: 22313-70-8
• Molecular Formula: C17H20N2O2S
• Molecular Weight: 316.424
• Mol File: 22313-70-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Thiourea, N,N'-bis[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N,N'-bis[(4-methoxyphenyl)methyl]-(22313-70-8)
• EPA Substance Registry System: Thiourea, N,N'-bis[(4-methoxyphenyl)methyl]-(22313-70-8)

Safety Data

• Hazardous Substances Data: 22313-70-8(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 2393-23-9 4-methoxy-benzylamine 
• 3694-57-3 1-(isothiocyanatomethyl)-4-methoxybenzene 
• 3717-21-3 (E)-4-methoxybenzaldoxime 

Downstream Products

• 1280723-00-3 3-(5-((3-(4-methoxybenzyl)-2-(4-methoxybenzylimino)-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid 
• 1280722-98-6 2-(4-((3-(4-methoxybenzyl)-2-(4-methoxybenzylimino)-4-oxothiazolidin-5-ylidene)methyl) phenoxy)acetic acid 
• 1280722-96-4 5-(4-hydroxybenzylidene)-3-(4-methoxybenzyl)-2-(4-methoxybenzylimino)thiazolidin-4-one 
• 57722-93-7 2,4-bis-(4-methoxy-benzyl)-3-thioxo-2,3,4,5-tetrahydro-benzo[e][1,3]diazepin-1-one 

Relevant articles and documents

Rapid and highly efficient synthesis of thioureas in biocompatible basic choline hydroxide

A straightforward and convenient synthesis of symmetrical thiourea derivatives by the reaction of primary amines and carbon disulfide in biocompatible basic choline hydroxide is presented. A variety of biologically important thiourea derivatives can be obtained in good to excellent yields without a tedious work-up under mild reaction conditions. A series of primary aliphatic and aromatic amines with different substituted functional groups have been converted to thiourea derivatives under milder reaction conditions and short reaction times.

Thiazolidione derivatives as novel antibiofilm agents: Design, synthesis, biological evaluation, and structure-activity relationships

Rational designed novel thiazolidiones were synthesized and evaluated for antibiofilm activity. The active derivatives were not only potent inhibitors of Staphylococcus epidermidis biofilm growth but also efficient antibacterial agents. 3f showed 4-fold higher activity (6.25 μM) in the biofilms dispersal assay and significantly higher antibacterial activity (MIC 3.125 μM) in comparison to the 3-(5-((6- (ethoxycarbonyl)-5-(benzo[1,3]dioxol-5-yl)-3-oxo-7- phenyl- thiazolo[3,2-a]pyrimidin-2(5H)-ylidene)methyl)furan-2-yl)benzoic acid (1).