2234-38-0

Basic information

• Product Name: 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid
• Synonyms: 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid
• CAS NO: 2234-38-0
• Molecular Weight: 367.358
• Mol File: 2234-38-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid(2234-38-0)
• EPA Substance Registry System: 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid(2234-38-0)

Safety Data

• Hazardous Substances Data: 2234-38-0(Hazardous Substances Data)

Upstream product

• 5410-10-6 dimethyl 2,2'-(acetylazanediyl)diacetate 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 
• 473401-85-3 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dicarboxylic acid dimethyl ester 
• 61780-18-5 methyl 2-amino-3-(4-methoxyphenyl) propanoate 
• 1186002-27-6 methyl α-(4-methoxybenzyl)diazoacetate 
• 1036355-83-5 3,4-bis-(4-methoxyphenyl)pyrrole-2,5-dicarboxylic acid monoethyl ester 
• 28030-16-2 3-(4-methoxyphenyl)-2-oxopropanoic acid 
• 1587692-61-2 ethyl 4-bromo-2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate 
• 1036356-17-8 ethyl 2-formyl-3-(4-methoxyphenyl)pyrrole-5-carboxylate 
• 1587692-53-2 4-bromo-5-formyl-1H-pyrrole-2-carboxylic acid ethyl ester 

Downstream Products

• 108774-82-9 3,4-bis(4-methoxyphenyl)-1H-pyrrole-2,5-dione 
• 1027899-57-5 3,4-bis-(4-methoxy-phenyl)-1H-pyrrole-2,5-dicarbonyl dichloride 
• 153212-84-1 Polycitone A 
• 272118-06-6 polycitone B 
• 470448-69-2 2,5-bis(4-methoxybenzoyl)-3,4-bis(4-methoxyphenyl)-1H-pyrrole 
• 470448-70-5 2,5-bis(4-hydroxybenzoyl)-3,4-bis(4-hydroxyphenyl)-1H-pyrrole 
• 470448-71-6 2,5-bis(4-acetoxy-3,5-dibromobenzoyl)-3,4-bis(4-acetoxy-3,5-dibromophenyl)-1H-pyrrole 
• 470448-72-7 2,5-bis(4-acetoxy-3,5-dibromobenzoyl)-3,4-bis(4-acetoxy-3,5-dibromophenyl)-1-[2-(4-acetoxyphenyl)ethyl]-1H-pyrrole 
• 2048-10-4 3,4-bis (4-methoxyphenyl)-1H-pyrrole 
• 1418216-89-3 3,4-bis[4-(benzyloxy)phenyl]-1H-pyrrole 

Relevant articles and documents

Total synthesis and biological evaluation of 7-hydroxyneolamellarin A as hypoxia-inducible factor-1α inhibitor for cancer therapy

7-Hydroxyneolamellarin A (7-OH-Neo A, 1), a natural marine product derived from sponge Dendrilla nigra, was first synthesized with 10% overall yield under the instruction of convergent synthetic strategy. We found that 7-OH-Neo A could attenuate the accum

Total synthesis and application of natural product of 7-hydroxy novel lamellarin A and analogues of natural product of 7-hydroxy novel lamellarin A

The invention belongs to the technical field of pharmaceutical and chemical engineering, and provides total synthesis and application of a natural product of 7-hydroxy novel lamellarin A and analoguesof the natural product of the 7-hydroxy novel lamellarin A. The invention provides the 7-hydroxy novel lamellarin A natural product and the series of analogues of the 7-hydroxy novel lamellarin A natural product. Tested compounds all have medium to good HIF-1 inhibitory activity, and have no market toxicity under the effective inhibition concentration of HIF-1 of the tested compounds, and it is indicated that the compounds have the potential for treating cancers by inhibiting transcription activating of the HIF-1.

Development of novel pyrrole synthesis for the preparation of intermediates of bioactive pyrrole alkaloids

We have developed a novel method for the synthesis of 3,4-diarylpyrrole-2,5-dicarboxylates via α-diazo esters, which are easily obtained from phenylalanine derivatives. Utilizing this method, intermediates of bioactive compounds having the structure of 3,