223575-42-6

Basic information

• Product Name: 2-(benzo[b]thiophen-3-yl)benzaldehyde
• Synonyms: 2-(benzo[b]thiophen-3-yl)benzaldehyde
• CAS NO: 223575-42-6
• Molecular Weight: 238.31
• Mol File: 223575-42-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(benzo[b]thiophen-3-yl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzo[b]thiophen-3-yl)benzaldehyde(223575-42-6)
• EPA Substance Registry System: 2-(benzo[b]thiophen-3-yl)benzaldehyde(223575-42-6)

Safety Data

• Hazardous Substances Data: 223575-42-6(Hazardous Substances Data)

Upstream product

• 113893-08-6 benzo[b]thiophen-3-yl-3-boronic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 7342-82-7 3-Bromothianaphthene 
• 40138-16-7 2-formylbenzene boronic acid 

Downstream Products

• 1065544-50-4 [2-(benzo[b]thien-3-yl)phenyl](phenyl)methanol 
• 1065544-52-6 [2-(benzo[b]thien-3-yl)phenyl](4-vinylphenyl)methanol 
• 1318261-75-4 6-(4-methoxyphenyl)benzo[b]naphtho[1,2-d]thiophene 
• 1318261-76-5 6-phenylbenzo[b]naphtho[1,2-d]thiophene 
• 1318261-56-1 3-(2-(2,2-dibromovinyl)phenyl)benzo[b]thiophene 

Relevant articles and documents

Regioselectivity-Switchable Intramolecular Hydroarylation of Ynone

The switchable catalytic approach to the regioselective intramolecular hydroarylation of ynone has been developed. When ZnI2 was used as catalyst, the umpolung α-arylation of ynone was realized via an addition-elimination process of iodine ion to generate the ortho-phenanthrenequinone methide (o-PQM), which could be trapped by styrene to form benzo[f,h]chromenes through hetero-Diels-Alder reaction. While IPrAuCl/AgSbF6 was applied, however, the β-arylation of ynone took place to afford benzocycloheptene-5-ones in moderate to excellent yields. (Figure presented.).

Construction of pinpoint-fluorinated benzothiophene frameworks using palladium-catalyzed cyclization of o-(fluorovinyl)phenyl-substituted thiophenes

o-(2,2-Difluorovinyl)phenyl- or o-(1,2,2-trifluorovinyl)phenylsubstituted thiophenes underwent palladium(II)-catalyzed Friedel-Crafts-type cyclization on the fluorovinyl moieties to construct regioselectively monofluorinated or difluorinated benzothiophene frameworks (pinpoint-fluorinated naphtho[b]thiophenes). The cyclization of less nucleophilic 2-substituted thiophenes was effectively promoted by the addition of a CuOTf complex. Cyclization was also conducted in a tandem process, which facilitated the rapid synthesis of higher-order pinpoint-fluorinated PAHs (polycyclic aromatic hydrocarbons) bearing thiophene rings. Furthermore, cyclization was applied to the corresponding furan systems, which led to pinpoint-fluorinated naphtho[b]furans.

A general and efficient synthesis of substituted fluorenes and heterocycle-fused indenes containing thiophene or indole rings utilizing a Suzuki-Miyaura coupling and acid-catalyzed Friedel-Crafts reactions as key steps

A general and efficient synthesis of fluorenes or heterocycle-fused indenes including 3-thia-cyclopenta[a]indenes, 9-thia-indeno[1,2-a]indenes, 5,6-dihydroindeno[2,1-b]indoles has been developed. This methodology is realized by a multistep protocol involv