22374-48-7

Basic information

• Product Name: 2-Aminocyclohexanone
• Synonyms: 2-Aminocyclohexanone
• CAS NO: 22374-48-7
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.1576
• Mol File: 22374-48-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 213.9 °C at 760 mmHg
• Flash Point: 83.2 °C
• Appearance: /
• Density: 1.023 g/cm³
• CAS DataBase Reference: 2-Aminocyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Aminocyclohexanone(22374-48-7)
• EPA Substance Registry System: 2-Aminocyclohexanone(22374-48-7)

Safety Data

• Hazardous Substances Data: 22374-48-7(Hazardous Substances Data)

Usage

General Description

2-Aminocyclohexanone, also known as N-aminocyclohexanone, is an organic compound with the chemical formula C6H11NO. It is a cyclic amine and a ketone, containing a six-membered ring with an amino group attached to one of the carbon atoms. 2-Aminocyclohexanone is commonly used as a building block in the synthesis of various pharmaceuticals and fine chemicals. It is also employed as a reagent in organic synthesis, particularly in the preparation of heterocyclic compounds. The compound has a slightly ammonia-like odor and is typically a colorless to pale yellow liquid at room temperature. It is important to handle 2-Aminocyclohexanone with caution as it can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 24858-28-4 cyclohexane-1,2-dione monooxime 
• 25084-40-6 C₇H₁₂Cl₂N₂O 
• 108-94-1 cyclohexanone 
• 58101-72-7 C₈H₁₅ClOSi 
• 1638623-33-2 1-(cyclohex-1-en-1-yloxy)-1,1-dimethyl-N,N-bis(trimethylsilyl)silanamine 
• 6850-38-0 2-aminocyclohexanol 

Downstream Products

• 137858-58-3 2-benzamidocyclohexanone 
• 83196-02-5 2-<(Diphenylmethylidene)amino>cyclohexanone 
• 83196-04-7 (1S,2R)-2-(Benzhydryl-amino)-1-(1-phenyl-vinyl)-cyclohexanol 
• 83196-04-7 (1R,2R)-2-(Benzhydryl-amino)-1-(1-phenyl-vinyl)-cyclohexanol 
• 1268726-07-3 2-methoxy-6-methylsulfanyl-N-(2-oxo-cyclohexyl)-4-trifluoromethyl-benzamide 

Relevant articles and documents

Method for preparing alicyclic ketone by catalytic oxidation of alicyclic alcohol compound

The invention provides a method for preparing alicyclic ketone by catalytic oxidation of an alicyclic alcohol compound. The method takes air or oxygen as an oxidant and uses a catalyst system consisting two components of aza-adamantane free radical of nitroxide and a vanadium oxygen compound, and the alicyclic alcohol compound is oxidated into the corresponding alicyclic ketone with high selectivity at 50 to 120 DEG C. Compared with 2,2,6,6,-tetramethyl piperidine free radical of nitroxide, the aza-adamantane free radical of nitroxide has smaller influence of steric hindrance in a catalytic oxidation secondary alcohol reaction, and the catalyst system consisting of the vanadium oxygen compound has higher alicyclic alcohol oxidating efficiency. Compared with the conventional stoichiometric chemistry oxidation methods such as manganese dioxide, chromium trioxide and sodium hypochlorite, the method provided by the invention has the characteristics of few side products, mild reaction conditions, small environmental pollution and the like, and has very high practicability and economical efficiency.