224817-03-2 Usage
Description
6-chloro-N-phenyl-nicotinamide, also known as 6-chloronicotinoylphenylamide, is a chlorinated derivative of nicotinamide, an amide of nicotinic acid. It has a molecular formula of C12H9ClN2O and is a chemical compound used in various research and industrial applications.
Uses
Used in Pharmaceutical and Agrochemical Industries:
6-chloro-N-phenyl-nicotinamide is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, contributing to the development of new drugs and agricultural products.
Used in Material Development:
6-chloro-N-phenyl-nicotinamide may have potential uses in the development of new materials, indicating its versatility and applicability in creating innovative substances.
Used as a Reagent in Organic Chemistry Reactions:
6-chloro-N-phenyl-nicotinamide also serves as a reagent in organic chemistry reactions, facilitating various chemical processes and syntheses.
Safety Note:
It is important to handle 6-chloro-N-phenyl-nicotinamide with care, as it may pose health and environmental risks if not properly managed, highlighting the need for proper safety measures during its use and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 224817-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,4,8,1 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 224817-03:
(8*2)+(7*2)+(6*4)+(5*8)+(4*1)+(3*7)+(2*0)+(1*3)=122
122 % 10 = 2
So 224817-03-2 is a valid CAS Registry Number.
224817-03-2Relevant articles and documents
Synthesis, computational predictions of selective bioactive nicotinamide derivatives and in vitro biological evaluations
Thirunavukarasu, Jayaprakash,Begam, Rosina,Shajahan
, p. 518 - 526 (2019/07/09)
A series of nicotinamide derivatives were designed and studied in silico molecular docking predictions against inflammatory responsible enzymes (cyclooxygenase-1(1PGG) and cyclooxygenase-2 (4-COX)). The well-predicted compounds were synthesized, characterized by the spectroscopic techniques namely, Proton Nuclear Magnetic Resonance, Carbon Nuclear Magnetic Resonance and the in vitro biological studies namely, anti-inflammatory activity and anti-diabetic activity. Furthermore, Density Functional Theory Calculations and Frontier Molecular Orbital by molecular electrostatic potential were investigated.
DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS
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Paragraph 0067; 0075, (2014/01/09)
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Diacylglycerol Acyltransferase Inhibitors
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Page/Page column 13-14, (2010/05/13)
Provided herein are compounds of the formula (I): were R1 is phenyl, R2 is hydrogen, halogen or lower alkyl, X is carbon on nitrogen, and R3 is isoquinoline, -amino, or a 4- to 6-membered heterocycloalkyl ring and pharmaceutically acceptable salts thereof, which are active as DGAT inhibitors and therefore find uses in treatment of diseases associated with abnormal metabolism of triglicerides such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
