22511-42-8

Basic information

• Product Name: Benzoic acid, 2-(2-ethoxy-2-oxoethoxy)-, methyl ester
• CAS NO: 22511-42-8
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Mol File: 22511-42-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(2-ethoxy-2-oxoethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2-ethoxy-2-oxoethoxy)-, methyl ester(22511-42-8)
• EPA Substance Registry System: Benzoic acid, 2-(2-ethoxy-2-oxoethoxy)-, methyl ester(22511-42-8)

Safety Data

• Hazardous Substances Data: 22511-42-8(Hazardous Substances Data)

Upstream product

• 69-72-7 salicylic acid 
• 105-39-5 chloroacetic acid ethyl ester 
• 119-36-8 methyl salicylate 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 635-53-0 (2-carboxyphenoxy)acetic acid 
• 208711-51-7 benzofuran-3(2H)-one O-methyloxime 
• 208711-51-7 benzofuran-3(2H)-one O-methyloxime 
• 40620-00-6 3-chlorobenzo[b]furan-2-carbaldehyde 
• 169153-13-3 E-(5,6-dihydro-[1,4,2]dioxazin-3-yl)-(2-hydroxy-phenyl)-methanone O-methyl-oxime 
• 169153-14-4 (E)-(5,6-dihydro-[1,4,2]dioxazin-3-yl)-(2-hydroxyphenyl)-methanone O-methyloxime 
• 208711-58-4 benzofuran-3(2H)-one O-methyl oxime 
• 132207-27-3 2-(1H-Benzoimidazol-2-ylmethoxy)-benzoic acid; hydrochloride 

Relevant articles and documents

COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR

The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.

PROCESS FOR PREPARING (E)-(5,6-DIHYDRO-1,4,2-DIOXAZINE-3-YL) (2-HYDROXYPHENYL) METHANONE O-METHYL OXIME

A process for preparing (E)-(5,6-dihydro-l,4,2-dioxazin-3-yl)(2- hydroxyphenyl)methanone O-methyl oxime is described which includes: (i) reacting benzofuran-3(2H)-one O-methyl oxime (1) with at least one nitrite selected from n-butyl nitrite and tert-butyl nitrite, in the presence of a metal alkoxide to form (2Z,32)-2,3-benzofuran-dione O3-methyl dioxime (2) as the predominant isomer; (ii) reacting the (2Z,3Z)-2,3-benzofuran-dione O -methyl dioxime (2) with 2- haloethanol to form (2Z,3Z)-benzofuran-2,3-dione 02-(2-hydroxyethyl) O3 -methyl dioxime (3); and (iii) reacting the (2Z,3Z)-benzofuran-2,3-dione 02-(2-hydroxyethyl) and -methyl dioxime (3) with an acid to form (E)-(5,6-dihydro-l,4,2-dioxazin-3-yl)(2- hydroxyphenyl)methanone (9-methyl oxime (4);

BENZOFURANYL- AND BENZOTHIENYL- PIPERAZINYL QUINOLINES AND METHODS OF THEIR USE

Benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives and compositions containing such compounds are disclosed. Methods of using benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives and compositions containing such composition in the treatment and/or prevention of serotonin-related disorders, such as depression and anxiety, are also disclosed. In addition, processes for the preparation of benzofuranyl- and benzothienyl-piperzinyl quinoline derivatives are disclosed.