226885-87-6Relevant articles and documents
Enantioselective synthesis of phyllanthurinolactone, a leaf-closing substance of Phyllanthus urinaria L., and its analogs toward the development of molecular probes
Urakawa, Yoshifumi,Sugimoto, Takanori,Sato, Hirotaka,Ueda, Minoru
, p. 5885 - 5888 (2004)
We report enantioselective synthesis of phyllanthurinolactone (1), a leaf-closing substance of Phyllanthus urinaria L., and its analogs with sugars other than D-glucose. Structure-activity relationship study using them revealed that the structure of the sugar moiety did not affect their bioactivity at all. This result is very important for the development of molecular probes based on the structure of 1.