227000-85-3

Basic information

• Product Name: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine
• Synonyms: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine
• CAS NO: 227000-85-3
• Molecular Formula: C₂₃H₃₂ClNO
• Molecular Weight: 373.95928
• Mol File: 227000-85-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-47°C
• Boiling Point: 461.3±55.0 °C(Predicted)
• Flash Point: >110℃
• Appearance: /
• Density: 1.043±0.06 g/cm3(Predicted)
• Storage Temp.: ?20°C
• PKA: 2.78±0.70(Predicted)
• CAS DataBase Reference: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(227000-85-3)
• EPA Substance Registry System: N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine(227000-85-3)

Safety Data

• Hazard Codes: O,C
• Statements: 8-34
• Safety Statements: 17-26-36/37/39-45
• RIDADR: UN 3085 8(5.1) / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 227000-85-3(Hazardous Substances Data)

Usage

Description

N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine is a complex organic compound with a unique molecular structure. It is characterized by its hydroxylamine functional group and a series of alkyl and aryl substituents. N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine is synthesized using a commercially available NMP initiator, as described by Prof. Karen Wooley, and is likely to have various applications in the field of chemistry, particularly in the synthesis of block copolymers.

Uses

Used in Block Copolymer Synthesis:
N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine is used as a key component in the synthesis of block copolymers. Its unique molecular structure allows for the formation of novel copolymers with tailored properties, making it a valuable asset in the field of polymer chemistry.
Used in the Polymer Industry:
In the polymer industry, N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine is used as a monomer for the production of block copolymers. These copolymers can be utilized in various applications, such as in the creation of advanced materials with improved mechanical, thermal, and chemical properties.
Used in the Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, the complex structure of N-tert-Butyl-O-[1-[4-(chloroMethyl)phenyl]ethyl]-N-(2-Methyl-1-phenylpropyl)hydroxylaMine suggests that it may have potential applications in the pharmaceutical industry. Its unique molecular architecture could be exploited for the development of new drugs or drug delivery systems, targeting specific biological pathways or receptors.

Upstream product

• 1592-20-7 4-Vinylbenzyl chloride 
• 61015-94-9 N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)-N-oxyl 
• 85664-55-7 (Z)-2-methyl-N-(2-methylpropylidene)propan-2-amine N-oxide 

Downstream Products

• 325468-29-9 2,2,5-trimethyl-3-(1'-(4''-acetoxymethyl)phenylethoxy)-4-phenyl-3-azahexane 
• 393110-71-9 O-(1-(4-(azidomethyl)phenyl)ethyl)-N-(tert-butyl)-N-(2-methyl-1-phenylpropyl)hydroxylamine 
• 895583-67-2 2,2,5-trimethyl-3-(1-(4-dioctylphosphorylmethyl)phenylethoxy)-4-phenyl-3-azahexane 
• 433266-98-9 2,2,5-trimethyl-3-(1'-(4''-hydroxymethyl)phenylethoxy)-4-phenyl-3-azahexane 
• 293328-23-1 2,2,5-trimethyl-3-(1'-p-aminomethylphenylethoxy)-4-phenyl-3-azahexane 
• 496816-88-7 2,2,5-trimethyl-3-(1'-p-(t-butyloxycarbonylamino)methylphenylethoxy)-4-phenyl-3-azahexane 
• 496816-90-1 2,2,5-trimethyl-3-(1'-p-((S)-(-)-2''-(t-butyl-oxy-carbonylamide)-3''-(p-oxyphenyl)-1'',1''-diphenylpropan-1''-ol)benzylethoxy)-4-phenyl-3-azahexane 
• 1000372-07-5 N-tert-butyl-O-[1-(4-cholesterolmethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine 
• 1000372-06-4 N-tert-butyl-O-[1-(4-iodomethyl-phenyl)-ethyl]-N-(2-methyl-1-phenyl-propyl)-hydroxylamine 
• 1037074-91-1 C₄₄H₅₁NO₂S₂ 
• 1079398-21-2 4-(1-(tert-butyl(2-methyl-1-phenylpropyl)aminooxy)ethyl)benzyl dodecyl carbonotrithioate 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR POLYMER-CAGED LIPOSOMES

The present invention provides liposomal compositions and methods of using such compositions in vitro and in vivo. In particular, the present invention provides stable, polymer-caged liposomes comprising a pH responsive delivery mechanism for delivery of

Development of a universal alkoxyamine for "living" free radical polymerizations

Examination of novel alkoxyamines has demonstrated the pivotal role that the nitroxide plays in mediating the "living" or controlled polymerization of a wide range of vinyl monomers. Surveying a variety of different alkoxyamine structures led to α-hydrido derivatives based on a 2,2,5-trimethyl-4-phenyl-3-azahexane-3-oxy, 1, skeleton which were able to control the polymerization of styrene, acrylate, acrylamide, and acrylonitrile based monomers. For each monomer set, the molecular weight could be controlled from 1000 to 200 000 amu with polydispersities typically 1.05-1.15. Block and random copolymers based on combinations of the above monomers could also be prepared with similar control. In comparison with 2,2,6,6-tetramethylpiperidinoxy (TEMPO), these new systems represent a dramatic increase in the range of monomers that can be polymerized under controlled conditions and overcome many of the limitations associated with nitroxide-mediated "living" free radical procedures. Monomer selection and functional group compatibility now approach those of ATRP-based systems.