22739-76-0 Usage
Description
2-Propanol-d8 (Isopropanol-d8) is a deuterated derivative of isopropanol, a colorless liquid. It is utilized in various scientific applications, particularly in chemical research and pharmaceuticals, due to its unique properties and reactivity.
Uses
Used in Chemical Research:
2-Propanol-d8 is used as a solvent and intermediate in chemical research for studying the generation and decay of correlated radical pairs (SCRP) during the reduction of acetone-d6 in 2-propanol-d8. It is also employed in the evaluation of triplet decay constants, triplet lifetime, and photoreduction rate constants of benzophenone through Fourier transform-electron paramagnetic resonance (FT-EPR) spectroscopy.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Propanol-d8 serves as an intermediate in the synthesis of various compounds and药物, contributing to the development of new drugs and therapeutic agents. Its deuterated nature provides unique insights into the chemical behavior and reactions of molecules, which can be crucial for optimizing pharmaceutical formulations and understanding their mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 22739-76-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,7,3 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22739-76:
(7*2)+(6*2)+(5*7)+(4*3)+(3*9)+(2*7)+(1*6)=120
120 % 10 = 0
So 22739-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H8O/c1-3(2)4/h3-4H,1-2H3/i1D3,2D3,3D,4D
22739-76-0Relevant articles and documents
DEUTERIUM-SUBSTITUTED OXADIAZOLES
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Paragraph 00179, (2016/10/31)
Described are deuterated modulators of S1P1 receptors, pharmaceutical compositions thereof, and methods of use thereof.
Simple and efficient catalytic reaction for the selective deuteration of alcohols
Khaskin, Eugene,Milstein, David
, p. 448 - 452 (2013/08/25)
A highly efficient system for the catalytic deuteration of α and β CH bonds of primary and secondary alcohols has been developed. The deuterium source is D2O. Together with the low catalyst loadings and the simple experimental setup, the reaction has direct application to the synthesis of bioactive isotopologues and the direct synthesis of fully deuterated substrates, such as ethanol-d6. The current system represents a significant advance in practicality for homogeneous metal catalyzed systems that carry out H/D exchange in organic substrates with water.
Iridium-catalyzed H/D exchange into organic compounds in water
Klei, Steven R.,Golden, Jeffrey T.,Tilley, T. Don,Bergman, Robert G.
, p. 2092 - 2093 (2007/10/03)
The air-stable complex Cp*(PMe3)IrCl2 efficiently catalyzes the exchange of deuterium from D2O into both activated and unactivated C-H bonds of organic molecules without added acid or stabilizers. Selectivity is observed in many cases, with activation of primary C-H bonds occurring preferentially. A number of new stoichiometric transformations involving the iridiym catalyst precursor are also presented, including an ozidation-decarbonylation reaction with primary alcohols. Copyright