22817-26-1

Basic information

• Product Name: 2,3-DIHYDRO-1H-BENZ[DE]ISOQUINOLINE
• Synonyms: 1,8-NAPHTHALMETHYLAMINE;2,3-DIHYDRO-1H-BENZ[DE]ISOQUINOLINE;2,3-Dihydro-1H-benzdeüisoquinoline, 97%;2,3-Dihydro-1H-benzo[de]isoquinoline
• CAS NO: 22817-26-1
• Molecular Formula: C₁₂H₁₁N
• Molecular Weight: 169.22
• EINECS: -0
• Mol File: 22817-26-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 100-102°C
• Boiling Point: 120°C 0,5mm
• Flash Point: 120°C/0.5mm
• Appearance: /
• Density: 1.138
• Vapor Pressure: 0.000125mmHg at 25°C
• Refractive Index: 1.661
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.32±0.20(Predicted)
• BRN: 134303
• CAS DataBase Reference: 2,3-DIHYDRO-1H-BENZ[DE]ISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1H-BENZ[DE]ISOQUINOLINE(22817-26-1)
• EPA Substance Registry System: 2,3-DIHYDRO-1H-BENZ[DE]ISOQUINOLINE(22817-26-1)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3259
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 22817-26-1(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1H-benz[de]isoquinoline is a heterocyclic organic compound with the chemical formula C14H13N. It is a polycyclic aromatic hydrocarbon with a bicyclic structure containing a benzene ring fused to an isoquinoline ring. 2,3-Dihydro-1H-benz[de]isoquinoline is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. It is also a known precursor in the synthesis of alkaloids and has been studied for its potential medical applications, including its activity as an anti-tumor agent. However,

InChI:InChI=1/C12H11N/c1-3-9-4-2-6-11-8-13-7-10(5-1)12(9)11/h1-6,13H,7-8H2

Upstream product

• 81-83-4 1,8-Naphthalimide 
• 65448-54-6 2,3-dihydro-(2-phenylmethyl)-1H-benz[de]isoquinoline 
• 2896-24-4 N-benzyl-1,8-naphthalimide 
• 81-84-5 1,8-Naphthalic anhydride 

Downstream Products

• 81585-11-7 N-(4-Methoxy-phenyl)-1H,3H-benzo[de]isoquinoline-2-carboxamidine 
• 253442-64-7 1,3-Dihydro-2-((4-(4-fluorophenyl)-4-oxobutyl))-1H-benz[de] isoquinoline 
• 508236-61-1 8-(2,3-Dihydro-1H-benzo[de]isoquinolin-2-ylmethyl)-5-(3,4-dimethoxybenzylamino)-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine 

Relevant articles and documents

Synthesis, characterization, and coordination chemistry of the 2-azaphenalenyl radical

The 2-azaphenalenyl radical 2 has been synthesized and characterized by ESR spectroscopy. Variable-temperature ESR measurements were carried out on both the phenalenyl (1) and the 2-azaphenalenyl (2) radicals. The phenalenyl radical 1 has the known propen

Piperadinyl-substituted pyridylalkane, alkene and alkine carboxamides

The invention relates to new piperidinyl-substituted pyridyl carboxamides of the general formula (I), wherein the structure element E has meanings (E1) or (E2) and whereby the heterocyclic ring can optionally have a double bond. These substances have especially high cytostatic activities and pronounced immunosuppressive properties which make them suitable for therapeutic treatment in broad tumor spectrum.

Asymmetric synthesis catalyzed by chiral ferrocenylphosphine transition metal complexes. 10 gold(I)-catalyzed asymmetric aldol reaction of isocyanoacetate

Optically active ferrocenylbisphosphine ligands containing 2-(dialkylamino)ethylamino group on the ferrocenylmethyl position have been prepared and used for the gold(I)-catalyzed asymmetric aldol reaction of isocyanoacetate with aldehydes. Six-membered ring amines, such as morpholino or piperidino group, at the terminal of the side chain were most stereoselective to give optically active trans-4- methoxycarbonyl-5-alkyl-2-oxazolines (up to 97% ee) with high enantio- and diastereoselectivity in a quantitative yield.