22849-48-5

Basic information

• Product Name: Z-Gly-S-Ala-S-Leu-OBzl
• Synonyms: Z-Gly-S-Ala-S-Leu-OBzl
• CAS NO: 22849-48-5
• Molecular Weight: 483.565
• Mol File: 22849-48-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Z-Gly-S-Ala-S-Leu-OBzl(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Gly-S-Ala-S-Leu-OBzl(22849-48-5)
• EPA Substance Registry System: Z-Gly-S-Ala-S-Leu-OBzl(22849-48-5)

Safety Data

• Hazardous Substances Data: 22849-48-5(Hazardous Substances Data)

Upstream product

• 3079-63-8 (S)-2-(2-Benzyloxycarbonylamino-acetylamino)-propionic acid 
• 1738-77-8 L-leucine benzyl ester p-toluenesulfonate 
• 2462-35-3 L-leucine benzyl ester hydrochloride 
• 1738-69-8 L-Leucine benzyl ester 
• 2899-60-7 Cbz-Gly-ONSuc 
• 113304-73-7 IPAoc-Ala-Leu-OBzl 

Relevant articles and documents

Effect of Tertiary Bases on O-Benzotriazolyluronium Salt-Induced Peptide Segment Coupling

Collidine activation of O-(7-azabenzotriazolyl)uronium salts leads to relatively low levels of racemization in the coupling of peptide segments, especially with reagents derived from 1,1-carbonyldipyrrolidine

1-ISOPROPYLALLYLOXYCARBONYL (IPAoc) AS A PROTECTIVE GROUP OF AMINES AND ITS DEPROTECTION CATALYSED BY PALLADIUM-PHOSPHINE COMPLEX

As a new protective group of amines, 1-isopropylallyloxycarbonyl (IPAoc) group was developed.IPAoc group can be removed by treatment with a palladium-phosphine catalyst forming carbon dioxide and 4-methyl-1,3-pentadiene by the decarboxylation and β-hydrogen elimination of (?-1-isopropylallyl)-palladium intermediate under neutral condititons.The present protection-deprotection was applied to a one-pot peptide synthesis.

Racemization-Free Photochemical Coupling of Peptide Segments

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