228873-97-0

Basic information

• Product Name: Silanol, dimethyl[4-(trifluoromethyl)phenyl]-
• CAS NO: 228873-97-0
• Molecular Formula: C9H11F3OSi
• Molecular Weight: 220.266
• Mol File: 228873-97-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Silanol, dimethyl[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silanol, dimethyl[4-(trifluoromethyl)phenyl]-(228873-97-0)
• EPA Substance Registry System: Silanol, dimethyl[4-(trifluoromethyl)phenyl]-(228873-97-0)

Safety Data

• Hazardous Substances Data: 228873-97-0(Hazardous Substances Data)

Upstream product

• 402-43-7 p-trifluoromethylphenyl bromide 
• 1415919-37-7 dimethyl(4-trifluoromethylphenyl)silyl formate 
• 19254-78-5 dimethyl(4-trifluoromethylphenyl)silane 
• 541-05-9 Hexamethylcyclotrisiloxane 

Downstream Products

• 220466-27-3 n-butyl trans-4-trifluoromethylcinnamate 
• 920015-51-6 potassium (4-(trifluoromethyl)phenyl)dimethylsilanololate 
• 334874-12-3 trans-Pt(C₆H₄CF₃-4)2(PEt₃)2 
• 47230-38-6 diethyl biphenyl-4,4'-dicarboxylate 
• 647842-34-0 ethyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate 
• 10355-12-1 1-(4-methoxyphenyl)-4-(trifluoromethyl)benzene 
• 2132-80-1 4,4'-Dimethoxybiphenyl 
• 581-80-6 4,4'-bis(trifluoromethyl)biphenyl 
• 132312-99-3 1-methoxy-4-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene 
• 364377-56-0 trans-[Pt(Ph)(OSiMe₂(C₆H₄CF₃-4))(PPh₃)2] 
• 364377-51-5 trans-[Pt(p-CF₃C₆H₄)(I)(PPh₃)2] 

Relevant articles and documents

Selective Manganese-Catalyzed Oxidation of Hydrosilanes to Silanols under Neutral Reaction Conditions

The first manganese-catalyzed oxidation of organosilanes to silanols with H2O2 under neutral reaction conditions has been accomplished. A variety of organosilanes with alkyl, aryl, alknyl, and heterocyclic substituents were tolerated, as well as sterically hindered organosilanes. The oxidation appears to proceed by a concerted process involving a manganese hydroperoxide species. Featuring mild reaction conditions, fast oxidation, and no waste byproducts, the protocol allows a low-cost, eco-benign synthesis of both silanols and silanediols.

Diamond-shaped [Ag4]4+ cluster encapsulated by silicotungstate ligands: Synthesis and catalysis of hydrolytic oxidation of silanes

An Ag4 diamond is encapsulated by silicotungstate ligands in TBA8[Ag4(DMSO)2(γ-H2SiW 10O36)2]·2 DMSO·2 H2O (Ag4; DMSO=dimethyl sulfoxide, TBA=tetra-n-butylammonium), which was obtained by reaction of TBA4H4[γ-SiW10O 36] with AgOAc in an organic medium. Polyoxometalate Ag4 (see picture) selectively catalyzes hydrolytic oxidation of various silanes to the corresponding silanols in high yields (72-96 %). Copyright

Cross-coupling reactions of aromatic and heteroaromatic silanolates with aromatic and heteroaromatic halides

The alkali-metal salts (potassium and sodium) of a large number of aryl- and heteroarylsilanols undergo efficient cross-coupling with a wide range of aromatic bromides and chlorides under mild conditions to form polysubstituted biaryls. The critical feature for the success of these coupling reactions and their considerable scope is the use of bis(tri-tert-butylphosphine)palladium. Under the optimized conditions, electron-rich, electron-poor, and sterically hindered arylsilanolates afford cross-coupling products in good yields. Many functional groups are compatible with the coupling conditions such as esters, ketones, acetals, ethers, silyl ethers, and dimethylamino groups. Two particularly challenging substrates, (2-benzofuranyl)dimethylsilanolate and (2,6-dichlorophenyl)dimethylsilanolate prepared as their sodium salts showed excellent activity in the coupling reactions, in the former case also with aromatic chlorides. General methods for the efficient synthesis of a wide range of aromatic silanols are also described.