22906-18-9Relevant articles and documents
Stereospecific Nucleophilic Substitution of Enantioenriched Tertiary Benzylic Amines via in Situ Activation with Benzyne
Gui, Yang,Tian, Shi-Kai
, p. 1554 - 1557 (2017/04/13)
A one-pot protocol has been developed for sequential benzyne activation and nucleophilic substitution of enantioenriched tertiary benzylic amines. In the presence of 2-(trimethylsilyl)phenyl triflate and CsF, a range of enantioenriched tertiary benzylic amines were substituted by various nucleophiles, delivering structurally diverse benzylic compounds in moderate to excellent yields with excellent retention of enantiopurity. Importantly, this operationally simple protocol permitted formation of various chiral C-S, C-Se, C-C, and C-N bonds with excellent enantiopurity under metal-free conditions.
Lewis acid-catalyzed reduction of dithioacetals by 1,4-cyclohexadiene
Ikeshita, Kei-ichiro,Kihara, Nobuhiro,Sonoda, Motohiro,Ogawa, Akiya
, p. 3025 - 3028 (2008/02/06)
Dithioacetals were reduced by 1,4-cyclohexadiene in the presence of a catalytic amount of Lewis acid to afford the corresponding sulfides in good yields.
A Novel Catalyst System, Trimethylsilyl Chloride and Indium(III) Chloride, as an Efficient Catalyst in the Sulfide Synthesis
Mukaiyama, Teruaki,Ohno, Takashi,Nishimura, Takashi,Han, Jeong Sik,Kobayashi, Shu
, p. 2524 - 2527 (2007/10/02)
O-Trimethylsilyl monothioacetals, which are generally difficult to activate under acidic conditions due to their rapid disproportionation, smoothly react with triethylsilane in the presence of a novel catalyst system, trimethylsilyl chloride and indium(III) chloride, to afford the corresponding sulfides in good to high yields.One pot synthesis of sulfides from aldehydes is also attained in high yields by successive treatment of aldehydes with trimethylsilyl alkyl (aryl) sulfides and triethylsilane in the presence of the above catalyst system under extremely mild conditions.
