23046-03-9

Basic information

• Product Name: 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid
• Synonyms: 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid;5,6-dimethoxybenzo[b]thiophene-2-carboxylic acid
• CAS NO: 23046-03-9
• Molecular Formula: C₁₁H₁₀O₄S
• Molecular Weight: 238.26
• Mol File: 23046-03-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 255-257 °C
• Boiling Point: 424.7°Cat760mmHg
• Flash Point: 210.7°C
• Appearance: /
• Density: 1.372g/cm³
• Vapor Pressure: 5.69E-08mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: 2-8°C(protect from light)
• PKA: 3.52±0.30(Predicted)
• CAS DataBase Reference: 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid(23046-03-9)
• EPA Substance Registry System: 5,6-dimethoxy-1-benzothiophene-2-carboxylic acid(23046-03-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 23046-03-9(Hazardous Substances Data)

Usage

General Description

5,6-dimethoxy-1-benzothiophene-2-carboxylic acid is a compound classified under the broader category of benzothiophenes, which are sulfur-containing aromatic compounds. This particular compound has two methoxy groups, which are oxygen bound to a methyl group, attached to the fifth and sixth atoms in the benzothiophene ring and a carboxylic acid group at the second atom. The specifics of its physical and chemical properties are not widely documented, an indicator that it is not commonly used or studied. However, like other carboxylic acids, it likely has acidic properties, and like other benzothiophenes, it likely displays aromaticity, a special type of chemical stability.

InChI:InChI=1/C11H10O4S/c1-14-7-3-6-4-10(11(12)13)16-9(6)5-8(7)15-2/h3-5H,1-2H3,(H,12,13)

Upstream product

• 872284-72-5 3,4,3',4'-tetramethoxy-α,α'-disulfanediyl-di-cinnamic acid 
• 140-89-6 potassium ethyl xanthogenate 
• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 97852-94-3 β-(3,4-Dimethoxy-phenyl)-α-mercapto-acrylsaeure 
• 71924-62-4 2-fluoro-4,5-dimethoxybenzaldehyde 
• 35212-99-8 methyl 5,6-dimethoxybenzo[b]thiophene-2-carboxylate 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 20357-25-9 6-nitroveratraldehyde 

Downstream Products

• 91715-47-8 5,6-dimethoxybenzo[b]thiophene 
• 101042-57-3 5,6-Dimethoxybenzothiophen-2-nitrile 
• 35212-99-8 methyl 5,6-dimethoxybenzo[b]thiophene-2-carboxylate 
• 1295537-10-8 methyl 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoate 
• 126674-91-7 2-(5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 
• 1295537-09-5 2-(1,1-dioxo-5,6-dimethoxybenzo[b]thiophene-2-carboxamido)benzoic acid 

Relevant articles and documents

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Two synthetic methods were developed for the synthesis of PDE3A inhibitor ORG9935. The first one proceeds in six steps and 34% overall yield and the second one in five steps and an overall yield of 69% starting from commercially available starting materia

Benzothiophene compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application of benzothiophene compound or pharmaceutically acceptable salt and isomer thereof

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Benzothiophene amide compound and preparation method and application thereof

The invention relates to a benzothiophene amide compound and a preparation method and application thereof. Specifically, the present application relates to a compound represented by formula (I), a stereoisomer, a tautomer, a polymorph, an N-oxide, an isotope labeled compound, a metabolite or a prodrug thereof, or a solvate or a pharmaceutically acceptable salt thereof, and the compound can be usedfor preparing a drug for treating a cell proliferative disease.