2315-97-1

Basic information

• Product Name: LUCIGENIN
• Synonyms: lucigenin or N,N′-dimethyl-9,9′-biacridinium dinitrate;L-6868;NSC-151912;10,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research];9,9'-BIS(N-METHYLACRIDINIUM NITRATE);LUCIGENIN;BIS(N-METHYLACRIDINIUM) DINITRATE;BIS(N-METHYLACRIDINIUM) NITRATE
• CAS NO: 2315-97-1
• Molecular Formula: C₂₈H₂₂N₂*2NO₃
• Molecular Weight: 510.5
• EINECS: 219-023-4
• Product Categories: Miscellaneous Natural Products;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Acridinium (Chemiluminescence);Analytical Chemistry;Chemiluminescence;Acridine
• Mol File: 2315-97-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 250°C
• Appearance: Yellow powder with orange to brown cast/
• Solubility: acetic acid: soluble10mg/mL
• BRN: 3901768
• CAS DataBase Reference: LUCIGENIN(CAS DataBase Reference)
• NIST Chemistry Reference: LUCIGENIN(2315-97-1)
• EPA Substance Registry System: LUCIGENIN(2315-97-1)

Safety Data

• Safety Statements: 24/25
• RIDADR: 1479
• WGK Germany: 3
• HazardClass: 5.1
• PackingGroup: III
• Hazardous Substances Data: 2315-97-1(Hazardous Substances Data)

Usage

Description

Lucigenin is a chemiluminescent probe characterized by its dark yellow powder form. It is known for its ability to detect superoxide production and the presence of chloride in various biological systems. Lucigenin exhibits a bluish-green fluorescence and is also used as a fluorescent chloride-sensitive indicator, with its fluorescence being quenched by chloride.

Uses

Used in Chemiluminescence Applications:
Lucigenin is used as a chemiluminescent agent, producing a bluish-green fluorescence. This property makes it suitable for various applications, including the detection of dyes and metabolites.
Used in Detection of Peroxides in Biological Systems:
Lucigenin serves as a chemiluminescent probe for detecting peroxides in biological systems. It is a sensitive method applied to monitor superoxide production from various enzymatic and cellular sources, such as xanthine oxidase, microsomal NADPH cytochrome reductase, and NADPH oxidases of phagocytes, endothelial cells, fibroblasts, and smooth muscle cells of blood vessel walls.
Used in Detection of Superoxide Production:
Lucigenin is utilized to detect superoxide production by enzymatic and cellular sources. It has been applied in the study of superoxide production from different sources, providing valuable insights into the role of superoxide in various biological processes.
Used as a Fluorescent Chloride-Sensitive Indicator:
Lucigenin is also used as a fluorescent chloride-sensitive indicator, with its fluorescence being quenched by chloride. This property makes it useful for detecting the presence of chloride in various applications.
Used in Detection of Lipid Hydroperoxide in Oils:
Lucigenin reacts with hydrogen peroxide without generating free radical intermediates and has been used to detect lipid hydroperoxide in oils, making it a valuable tool in the food industry for assessing the quality and safety of oils.

Downstream Products

• 719-54-0 10-methyl-9, 10-dihydro-9-acridinone 
• 23663-77-6 10,10'-dimethyl-9,9'-biacridylidene 
• 75-07-0 acetaldehyde