231955-46-7Relevant articles and documents
Purine nucleoside analogues; 9: Benzylation of N2-acetyl-8- bromoguanine
Madre, Marina,Panchenko, Natella,Zhuk, Regina,Geenevasen, Jan A.,Van Den Burg, Alida,Koomen, Gerrit-Jan
, p. 775 - 778 (2007/10/03)
A one-step synthesis of regioisomeric N- and O-benzylated 8- bromoguanines 4, 5, 9, 10 via N2-acetyl-8-bromoguanine (2) is described. The possibility to prepare 8-oxo- and 8-chloroguanine derivatives 3, 11, 12 from the same compound 2 is demonstrated, 1H and 13C NMR spectra are used to locate the sites of aralkylation.