23197-88-8

Basic information

• Product Name: 3'-O-acetyl-2'-deoxyuridine
• Synonyms: 3'-O-acetyl-2'-deoxyuridine
• CAS NO: 23197-88-8
• Molecular Weight: 270.242
• Mol File: 23197-88-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3'-O-acetyl-2'-deoxyuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-acetyl-2'-deoxyuridine(23197-88-8)
• EPA Substance Registry System: 3'-O-acetyl-2'-deoxyuridine(23197-88-8)

Safety Data

• Hazardous Substances Data: 23197-88-8(Hazardous Substances Data)

Upstream product

• 121356-00-1 3'-O-acetyl-2'-deoxy-5'-O-triphenylmethyluridine 
• 100-51-6 benzyl alcohol 
• 1140622-65-6 3'-O-acetyl-5'-O-t-butyldimethylsilyl-2'-deoxyuridine 

Downstream Products

• 13030-62-1 3',5'-di-O-acetyl-2'-deoxyuridine 
• 208330-15-8 C₄₀H₄₂N₄O₁₂ 
• 208330-18-1 C₄₀H₄₂N₄O₁₂ 
• 964-26-1 2'-deoxyuridine-5'-monophosphate 

Relevant articles and documents

Protecting groups transfer: Unusual method of removal of tr and TBDMS groups by transetherification

The triphenylmethyl (Tr) group undergoes a transfer (transetherification or disproportionation) between the molecules of 5'-O-Tr-2'-deoxynucleosides in a process mediated by anhydrous sulfates of Cu+2, Fe+2, or Ni+2 to yield mixtures of 3',5'-bis-O-Tr and 3'-O-Tr products. If phenylmethanol is present in a reaction medium, detritylation results with concomitant formation of phenylmethyl triphenylmethyl ether. The behavior of t-butyldimethylsilyl (TBDMS) group in 5'-O-TBDMS-2'-deoxynucleosides is exactly the same. Such type of transetherifications was not observed before for the O-Tr and O-TBDMS groups. Copyright Taylor & Francis Group, LLC.