23220-67-9

Basic information

• Product Name: (E)-β-Morpholino acrylonitrile
• Synonyms: (E)-β-Morpholino acrylonitrile
• CAS NO: 23220-67-9
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• Mol File: 23220-67-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-β-Morpholino acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-β-Morpholino acrylonitrile(23220-67-9)
• EPA Substance Registry System: (E)-β-Morpholino acrylonitrile(23220-67-9)

Safety Data

• Hazardous Substances Data: 23220-67-9(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 3721-37-7 cis-β-chloroacrylonitrile 
• 871-29-4 trans-β-chloroacrylonitrile 
• 372-09-8 cyanoacetic acid 
• 122-51-0 orthoformic acid triethyl ester 
• 87429-52-5 (Z)-β-morpholino acrylonitrile 
• 58243-08-6 (E)-3-ethoxyacrylonitrile 

Downstream Products

• 926-61-4 3-oxopropanoic acid 
• 82936-41-2 1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carbonitrile 
• 128957-55-1 1-(3-Chloro-phenyl)-1H-[1,2,3]triazole-4-carbonitrile 
• 128957-56-2 1-(p-tolyl)-1H-1,2,3-triazole-4-carbonitrile 
• 82936-42-3 1-(4-bromophenyl)-1H-1,2,3-triazole-4-carbonitrile 
• 128957-54-0 1-(3-Nitro-phenyl)-1H-[1,2,3]triazole-4-carbonitrile 
• 136758-33-3 2-Morpholin-4-yl-5-oxo-4-(3-trifluoromethyl-phenyl)-4,5-dihydro-indeno[1,2-b]pyran-3-carbonitrile 
• 136758-32-2 2-(morpholin-4-yl)-4-(4-nitrophenyl)-5-oxo-4H-indeno<1,2-b>pyran-3-carbonitrile 
• 104433-15-0 1-morpholino-2-cyano-3-(2',3'-dichlorophenyl)-4-nitro-but-1-ene 
• 5915-16-2 7-amino-1,2,4-triazolo[1,5-a]pyrimidine 
• 113967-74-1 5-Amino-2-methylthio-1,2,4-triazolo<1,5-a>pyrimidine 
• 1196153-97-5 ethyl 7-aminopyrazolo[1,5-a]pyrimidine-3-carboxylate 

Relevant articles and documents

1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS

Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.

Arylazide additions to α- and β- aminoacrylonitriles: Synthesis of 5-amino and 4-cyano-1,2,3-triazoles. Kinetic study of the cycloaddition

Arylazides reacted with α-aminoacrylonitriles 1 (captodative olefins) to produce in excellant yields 5-amino-1-aryl-1,2,3-triazoles.HCN was spontaneously eliminated from the corresponding triazoline.Reaction of the same 1,3-dipoles with β-aminoacrylonitri

NUCLEOPHILIC SUBSTITUTION IN β-CHLOROACRYLONITRILES

Previously undescribed polyfunctional unsaturated nitriles were obtained by the action of a series of nucleophiles (secondary amines, acids, inorganic salts) on isomeric cis- and trans-β-chloroacrylonitriles in optimum media.The substitution of chlorine in the isomeric β-chloroacrylonitriles is nonstereoselective.