2346-07-8

Basic information

• Product Name: p-Toluenesulfonic acid 2,2-dimethylpropyl ester
• Synonyms: p-Toluenesulfonic acid 2,2-dimethylpropyl ester;p-Toluenesulfonic acid neopentyl ester;neopentyl 4-methylbenzenesulfonate
• CAS NO: 2346-07-8
• Molecular Formula: C₁₂H₁₈O₃S
• Molecular Weight: 242.3345
• Mol File: 2346-07-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 48-49 °C
• Boiling Point: 338°Cat760mmHg
• Flash Point: 158.2°C
• Appearance: /
• Density: 1.101g/cm³
• Vapor Pressure: 0.000197mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: p-Toluenesulfonic acid 2,2-dimethylpropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: p-Toluenesulfonic acid 2,2-dimethylpropyl ester(2346-07-8)
• EPA Substance Registry System: p-Toluenesulfonic acid 2,2-dimethylpropyl ester(2346-07-8)

Safety Data

• Hazardous Substances Data: 2346-07-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H18O3S/c1-10-5-7-11(8-6-10)16(13,14)15-9-12(2,3)4/h5-8H,9H2,1-4H3

Upstream product

• 75-84-3 2,2-dimethyl-propanol-1 
• 98-59-9 p-toluenesulfonyl chloride 
• 83634-80-4 N,N-dimethyl-2-<(2,2-dimethylpropoxy)sulfonyl>ethanaminium p-toluenesulfonate 
• 104-15-4 toluene-4-sulfonic acid 
• 212077-64-0 neopentyloxy(diphenyl)-λ⁶-sulfanenitrile 
• 75391-24-1 2,2-dimethylpropyl ethenesulfonate 
• 75391-29-6 neopentyl 2-(dimethylamino)ethanesulfonate 

Downstream Products

• 1679-08-9 2,2-dimethylpropylthiol 
• 51616-83-2 dineopentyl sulfide 
• 15501-33-4 neopentyl iodide 
• 6079-57-8 neopentyl methyl sulfide 
• 53333-76-9 2,2-dimethyl-propane-1-sulfonyl chloride 
• 80-48-8 methyl p-toluene sulfonate 
• 7210-80-2 neopentyl phenyl sulphide 
• 91-20-3 naphthalene 
• 75-28-5 Isobutane 
• 75-84-3 2,2-dimethyl-propanol-1 
• 134724-20-2 Neopentyl 2,4,6-tri-t-butylphenyl ether 
• 630-17-1 2,2-dimethylpropyl bromide 
• 104-15-4 toluene-4-sulfonic acid 
• 14034-62-9 4-methylanilinium p-toluenesulfonate 

Relevant articles and documents

Visible-Light-Induced Passerini Multicomponent Polymerization

Herein, we introduce an additive-free visible-light-induced Passerini multicomponent polymerization (MCP) for the generation of high molar mass chains. In place of classical aldehydes (or ketones), highly reactive, in situ photogenerated thioaldehydes are exploited along with isocyanides and carboxylic acids. Prone to side reactions, the thioaldehyde moieties create a complex reaction environment which can be tamed by optimizing the synthetic conditions utilizing stochastic reaction path analysis, highlighting the potential of semi-batch procedures. Once the complex MCP environment is understood, step-growth polymers can be synthesized under mild reaction conditions which—after a Mumm rearrangement—result in the incorporation of thioester moieties directly into the polymer backbone, leading to soft matter materials that can be degraded by straightforward aminolysis or chain expanded by thiirane insertion.

BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS

The present invention relates to compounds of the formula (I), wherein X, R, R1, R2, D, E1, E2, E3, E4, G1, G2, G3 and G4 have the meanings indicated in the claims, which are valuable pharmaceutical active compounds. They are inhibitors of the protease ca

Application of alkoxy-λ6-sulfanenitriles as strong alkylating reagents

Alkoxy-λ6-sulfanenitriles were found to be versatile alkylating reagents toward various nucleophiles bearing at least one proton such as methanol, phenol, thiophenols, carboxylic acids, ptoluenesulfonic acid, hydrochloric acid, and primary and secondary amines. Reactivity of the alkoxy group of the λ6-sulfanenitriles showed an opposite trend to the usual SN2 character, i.e. Me (la), Pr (1b), and Bu (1d) ? i-Pr (1c). In the presence of p-TsOH, alkyl tosylates were predominantly formed instead of the alkylation products of nucleophiles. In addition, even a sterically hindered substrate, neopentyloxy-λ6-sulfanenitrile, was found to undergo an SN2 reaction toward thiophenol without any rearrangement product to give neopentyl phenyl sulfide in good yield.