23511-08-2

Basic information

• Product Name: (-)-2t-phenyl-3t-benzoyl-cyclopropane-carboxylic acid-(1r)-methyl ester
• CAS NO: 23511-08-2
• Molecular Weight: 280.323
• Mol File: 23511-08-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (-)-2t-phenyl-3t-benzoyl-cyclopropane-carboxylic acid-(1r)-methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-2t-phenyl-3t-benzoyl-cyclopropane-carboxylic acid-(1r)-methyl ester(23511-08-2)
• EPA Substance Registry System: (-)-2t-phenyl-3t-benzoyl-cyclopropane-carboxylic acid-(1r)-methyl ester(23511-08-2)

Safety Data

• Hazardous Substances Data: 23511-08-2(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 67-56-1 methanol 
• 19158-66-8 1-(2-oxo-2-phenylethyl)tetrahydrothiophenium bromide 
• 582299-08-9 methyl 2-benzyl-3-bromo-4-oxo-4-phenylbutanoate 
• 6938-59-6 methyl-2-benzyl-4-oxo-4-phenylbutanoate 
• 342639-81-0 methyl 2-benzyl-3-(nitrooxy)-4-oxo-4-phenylbutanoate 
• 5633-34-1 (benzoylmethylene)dimethylsulfurane 
• 186581-53-3 diazomethane 
• 4727-41-7 dimethylsulfonioacetate 
• 17572-77-9 (3E)-1,4-diphenylbut-3-en-1-one 

Relevant articles and documents

Enantioselective cyclopropanation of enals by oxidative N-heterocyclic carbene catalysis

Carbene catalysed redox activation of α,β-unsaturated aldehydes is applied for generation of α,β-unsaturated acyl azoliums which undergo cyclopropanation upon reaction with a sulfur ylide and an alcohol to give the corresponding cyclopropanecarboxylic acid esters. With chiral carbenes good to excellent diastereo and enantioselectivities are obtained.

A new photochemical route to cyclopropanes

Especially highly substituted cyclopropanes can be produced with a new photochemical approach. Starting with aromatic ketones that bear a leaving group adjacent to the carbonyl carbon atom, photolysis leads to the formation of 1,3-diradicals, which efficiently cyclize to cyclopropanes (see scheme; Ms=MeSO2).