23612-36-4

Basic information

• Product Name: 3-BROMO-5-AZAINDOLE
• Synonyms: 3-BROMO-5-AZAINDOLE
• CAS NO: 23612-36-4
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.032
• Product Categories: Azaindole;Building Blocks
• Mol File: 23612-36-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 357°Cat760mmHg
• Flash Point: 169.7°C
• Appearance: /
• Density: 1.77g/cm³
• Vapor Pressure: 5.79E-05mmHg at 25°C
• Refractive Index: 1.727
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-BROMO-5-AZAINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-AZAINDOLE(23612-36-4)
• EPA Substance Registry System: 3-BROMO-5-AZAINDOLE(23612-36-4)

Safety Data

• Hazardous Substances Data: 23612-36-4(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-azaindole is a chemical compound with the molecular formula C7H5BrN2. It is a brominated derivative of azaindole, a heterocyclic compound with potential biological properties. 3-Bromo-5-azaindole has been studied for its potential applications in pharmaceutical and agrochemical industries. It has been reported to possess anti-inflammatory properties and has shown effectiveness as an intermediate in the synthesis of various pharmaceutical compounds. Additionally, it has also been investigated for its potential as a building block in the development of new drugs and crop protection agents.

InChI:InChI=1/C7H5BrN2/c8-6-4-10-7-1-2-9-3-5(6)7/h1-4,10H

Upstream product

• 271-34-1 5-azaindole 

Downstream Products

• 192189-16-5 tert-butyl 3-bromo-1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 192189-29-0 2-(5-azaindol-3-yl)-5,11-dihydro-11-ethyl-5-methyl-6H-dipyrido[3,2-b;2',3'-e][1,4]diazepin-6-one 
• 1334712-90-1 tert-butyl 3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 1334712-91-2 3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-75-9 3-(4-chlorophenyl)-1-(oxolan-3-ylmethyl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-76-0 tert-butyl 4-[3-(4-chlorophenyl)-1H-pyrrolo[3,2-c]pyridin-1-yl]piperidine-1-carboxylate 
• 1334712-93-4 tert-butyl 4-[3-(3,4-dichlorophenyl)-1H-pyrrolo[3,2-c]pyridin-1-yl]piperidine-1-carboxylate 
• 1334711-77-1 3-(4-chlorophenyl)-1-(oxolan-3-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-78-2 3-(4-chlorophenyl)-1-(oxan-4-yl)-1H-pyrrolo[3,2-c]pyridine 
• 1334711-82-8 4-[3-(3,4-dichlorophenyl)-1H-pyrrolo[3,2-c]pyridin-1-yl]piperidine hydrochloride 
• 1334711-83-9 1-{4-[3-(3,4-dichlorophenyl)-1H-pyrrolo[3,2-c]pyridin-1-yl]piperidin-1-yl}-2-hydroxyethan-1-one 

Relevant articles and documents

Practical regioselective bromination of azaindoles and diazaindoles

A mild and efficient synthesis of various 3-brominated azaindoles and diazaindoles was developed by regioselective halogenation of the parent systems. This practical and high-yielding transformation was achieved with copper(II) bromide in acetonitrile at

TRANSCRIPTIONAL ENHANCED ASSOCIATE DOMAIN (TEAD) TRANSCRIPTION FACTOR INHIBITORS AND USES THEREOF

Provided herein are compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, compositions, and mixtures thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing diseases (e.g., proliferative diseases (e.g., cancers, such as carcinoma, sarcoma, lung cancer, thyroid cancer, skin cancer, ovarian cancer, colorectal cancer, prostate cancer, pancreatic cancer, esophageal cancer, liver cancer, breast cancer)) in a subject. Provided are methods of inhibiting a TEAD transcription factors (e.g., TEAD1, TEAD2, TEAD3, TEAD4) in a subject.

NEW CRTH2 ANTAGONISTS

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.