23674-58-0Relevant articles and documents
Synthetic Route to Enaminones via Metal-Free Four-Component Sequential Reactions of Aryl Olefins with CHCl3, Et3N, and TBHP
Zhang, Jiantao,Zhou, Peng,Yin, Aiguo,Zhang, Shuhua,Liu, Weibing
, p. 8980 - 8986 (2021/06/30)
An efficient and modular strategy was used to obtain enaminones with a wide range of functional groupsviaa four-component sequential reaction. This reaction proceeded under mild conditions without a catalyst in one pot. Furthermore, the products could be transformed into thiadiazoles.
Silver-catalyzed efficient synthesis of enaminones from propargyl alcohols and amines
Li, Mengshun,Fang, Dongmei,Geng, Feng,Dai, Xianping
supporting information, p. 4747 - 4749 (2017/11/28)
Enaminones are used as the key intermediates to construct heterocyclic compounds with various bioactivities. In this study, a simple and efficient approach for the synthesis of enaminones via amination of propargyl alcohols was developed. Under the catalysis of Ag2CO3, the reaction proceeded smoothly to afford the desired products in good yields. Preliminary mechanism experiments showed that Ag2CO3 played an essential role in the procedure of the reaction.
Highly stereoselective synthesis of cis-β-enaminones mediated by diethyl azodicarboxylate
Xu, Xiaoliang,Du, Ping,Cheng, Dongping,Wang, Hong,Li, Xiaonian
supporting information; experimental part, p. 1811 - 1813 (2012/02/16)
Promoted by diethyl azodicarboxylate, a novel and highly stereoselective synthesis of cis-β-enaminones via oxidative dehydrogenation and hydration of the substituted propargylamines was realized. The possible mechanism was also proposed.
