23694-17-9 Usage
Description
Sultopride hydrochloride is a crystalline solid that functions as a dopamine D2-receptor antagonist. It is a pharmaceutical compound with significant applications in the medical field, particularly in the treatment of various psychological and neurological conditions.
Uses
Used in Pharmaceutical Industry:
Sultopride hydrochloride is used as an antipsychotic agent for the treatment of psychiatric disorders. It works by blocking dopamine D2 receptors in the brain, which helps in managing symptoms such as hallucinations, delusions, and agitation associated with schizophrenia and other psychotic conditions.
Used in Neurology:
Sultopride hydrochloride is also utilized in neurology as a therapeutic agent for conditions involving dopamine dysregulation, such as Parkinson's disease and Huntington's disease. By modulating dopamine receptor activity, it can help alleviate motor and cognitive symptoms in these patients.
Originator
Barnetil,Delagrange,France,1976
Manufacturing Process
A solution of 17.22 g of N-ethyl-α-aminomethylpyrrolidine in 360 ml of
pyridine is placed in a 1 l balloon flask. A solution of 3.51 g of phosphorus
trichloride in 40 ml of pyridine is added at ambient temperature. After the
mixture has been stirred for 1 hour, 10 g of 2-methoxy-5-ethylsulfonylbenzoic
acid is introduced. The mixture is heated under reflux for 4 ? hours. After
cooling, the solvent is evaporated under vacuum and the residue is dissolved
in 200 ml of 20% sodium hydroxide. The solution is extracted with 200 ml of
chloroform.The organic solution is dried and filtered and the solvent is evaporated under
vacuum; the residue is dissolved in 150 ml of ethanol and the solution is
acidified with hydrochloric acid. The hydrochloride is dried without heating and
recrystallized from 100 ml of absolute ethanol. 7.2 g of N-(1-ethyl-2-
pyrrolidyl-methyl-2-methoxy-5-ethylsulfonylbenzamide hydrochloride is
produced. Melting point: 190°C to 193°C.
Therapeutic Function
Neuroleptic
Check Digit Verification of cas no
The CAS Registry Mumber 23694-17-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,6,9 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 23694-17:
(7*2)+(6*3)+(5*6)+(4*9)+(3*4)+(2*1)+(1*7)=119
119 % 10 = 9
So 23694-17-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H26N2O4S.ClH/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3;/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20);1H
