23696-28-8

Basic information

• Product Name: Olaquindox
• Synonyms: N-(2-HYDROXYETHYL)-3-METHYL-2-QUINOXALINECARBOXAMIDE 1,4-DIOXIDE;OLAGUINDOX;OLAQUINDOX;2-(n-(2-hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid;2-quinoxalinecarboxamide,n-(2-hydroxyethyl)-3-methyl-,1,4-dioxide;bayernox;bayonox;bisergon
• CAS NO: 23696-28-8
• Molecular Formula: C₁₂H₁₃N₃O₄
• Molecular Weight: 263.25
• EINECS: 245-832-7
• Product Categories: Food and Feed Additive;Nitric Oxide Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;pharma raw material;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Alkaloids
• Mol File: 23696-28-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 209°C (dec.)
• Boiling Point: 406.49°C (rough estimate)
• Flash Point: >204.4oC
• Appearance: Pale yellow crystalline solid
• Density: 1.2755 (rough estimate)
• Refractive Index: 1.5290 (estimate)
• Storage Temp.: 0-6°C
• Solubility: DMSO (Slightly)
• PKA: 13.75±0.10(Predicted)
• CAS DataBase Reference: Olaquindox(CAS DataBase Reference)
• NIST Chemistry Reference: Olaquindox(23696-28-8)
• EPA Substance Registry System: Olaquindox(23696-28-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43-42
• Safety Statements: 36/37-22
• RTECS: VD1582000
• Hazardous Substances Data: 23696-28-8(Hazardous Substances Data)

Usage

Description

Olaquindox is an antibiotic and a swine growth regulator, which is an antibacterial derivative of quinoxaline. It is a pale yellow crystalline solid, used as a growth promoter for pigs and has various applications in the agricultural and pharmaceutical industries.

Uses

Used in Pig Breeding:
Olaquindox is used as a growth promoter in pig-breeding, enhancing the growth and development of pigs. It acts as a chemotherapeutic agent prophylactically used to lower the frequency of bacterial enteritis in pigs, thus improving their overall health and reducing the risk of disease.
Used in Pharmaceutical Industry:
Olaquindox is also used in the pharmaceutical industry as a photosensitizer, forming a reactive oxyziridine on exposure to light. However,

Contact allergens

Olaquindox is an antibacterial agent derivative of quinoxaline, used as a growth promoter of pigs. It can be found in Bayo-N-Ox? and Proquindox? and numerous other pig feeds. It is a photosensitizer that forms reactive photoproducts on light exposure. It can induce photoallergic contact dermatitis and persistent light reactions.

InChI:InChI=1/C12H13N3O4/c1-8-11(12(17)13-6-7-16)15(19)10-5-3-2-4-9(10)14(8)18/h2-5,16H,6-7H2,1H3,(H,13,17)

Upstream product

• 480-96-6 benzofurazan oxide 
• 24309-97-5 N-(2-hydroxyethyl)-3-oxobutanamide 
• 13297-18-2 2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide 

Downstream Products

• 1386335-19-8 C₁₂H₁₅N₃O₄ 
• 1266332-09-5 3-hydroxymethyl-1,4-dideoxyolaquindox 
• 1386335-25-6 C₁₂H₁₃N₃O₄ 
• 1031705-99-3 3-hydroxymethyl-1-deoxyolaquindox 
• 112158-56-2 2-methyl-3-quinoxaline 1-oxide 
• 112158-57-3 2-methyl-3-quinoxalin 4-oxide 
• 26964-60-3 3-methyl-2-hydroxylquinoxaline 1,4-dioxide 
• 14003-34-0 3-methylquinoxalin-2-ol 
• 90417-40-6 3-methyl-2-hydroxylquinoxaline 4-oxide 

Relevant articles and documents

An Improved and Efficient Synthesis of Quinoxalinecarboxamide 1,4-Dioxides from Benzofuroxan and Acetoacetamides in the Presence of Calcium Salts

An improved and efficient method for the preparation of the title compounds 3 is described.Thus, quinoxalinecarboxamide 1,4-dioxides 3 are synthesized in high yields by reaction of benzofuroxan 1 with acetoacetamides 2 in the presence of catalytic amounts of calcium salts and ethanolamine.The reaction is assumed to involve a chelate mechanism with 4 as intermediate.Side reactions are studied by means of HPLC and TLC.