23722-96-5

Basic information

• Product Name: 2-[(5-amino-6-chloropyrimidin-4-yl)amino]-4-(hydroxymethyl)cyclopentanol
• CAS NO: 23722-96-5
• Molecular Formula: C₁₀H₁₅ClN₄O₂
• Molecular Weight: 258.7047
• Mol File: 23722-96-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 512.7°C at 760 mmHg
• Flash Point: 263.9°C
• Density: 1.522g/cm³
• Vapor Pressure: 2.45E-11mmHg at 25°C
• Refractive Index: 1.696
• CAS DataBase Reference: 2-[(5-amino-6-chloropyrimidin-4-yl)amino]-4-(hydroxymethyl)cyclopentanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(5-amino-6-chloropyrimidin-4-yl)amino]-4-(hydroxymethyl)cyclopentanol(23722-96-5)
• EPA Substance Registry System: 2-[(5-amino-6-chloropyrimidin-4-yl)amino]-4-(hydroxymethyl)cyclopentanol(23722-96-5)

Safety Data

• Hazardous Substances Data: 23722-96-5(Hazardous Substances Data)

Usage

Cyclopentanol derivative

The compound is derived from cyclopentanol, a five-carbon cyclic alcohol.

Amino-pyrimidine moiety

The compound contains a pyrimidine ring with an amino group attached to it, which may contribute to its biological activity.

Hydroxymethyl group

A hydroxymethyl group (-CH2OH) is present in the compound, which can participate in hydrogen bonding and affect the compound's solubility and reactivity.

Potential pharmaceutical application

The compound has potential use in the development of antiviral or antiparasitic drugs due to its unique structure and functional groups.

Biological activity

The presence of chloropyrimidine and amino groups suggests that the compound may have biological activity, making it a target for drug development.

Further research and testing needed

To fully understand the properties and potential uses of the compound, additional research and testing are required.

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 68715-64-0 (+/-)-(1α,3α,4β)-3-amino-4-hydroxycyclopentanemethanol 
• 152279-17-9 (cis)-methyl 4-aminocyclopent-2-enecarboxylate 

Downstream Products

• 23722-97-6 (1R*,2R*,4S*)-2-(6-Amino-9H-purin-9-yl)-4-(hydroxymethy)lcyclopentanol 

Relevant articles and documents

(±)-3'-Deoxyaraaristeromycin via a surprising rearrangement

Hydrolysis of (±)-3β-acetoxy-4α-benzamido-1α-cyclopentanemethyl acetate (5) with 6 N hydrochloric acid has been found to give an amine in which the configuration at C-3 has been inverted. This conclusion was reached following conversion of the amine into (±)-3'-deoxyaraaristeromycin (8) by following a standard adenine formation process of (i) reaction with 5-amino-4,6-dichloropyrimidine, (ii) ring closure with diethoxymethyl acetate, and (iii) ammonolysis. Use of basic hydrolysis conditions with 5 led to the expected (±)-3'-deoxyaristeromycin (7).