23733-71-3

Basic information

• Product Name: 2-[(R)-5-Methyl-2-(1-methylethylidene)cyclohexylidene]hydrazinecarboxamide
• Synonyms: (R)-p-Menth-4(8)-en-3-one semicarbazone;(R)-p-Menth-4(8)-en-3-onesemicarbazone;2-[(R)-5-Methyl-2-(1-methylethylidene)cyclohexylidene]hydrazinecarboxamide;Pulegone semicarbazone
• CAS NO: 23733-71-3
• Molecular Formula: C₁₁H₁₉N₃O
• Molecular Weight: 209.29
• Mol File: 23733-71-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(R)-5-Methyl-2-(1-methylethylidene)cyclohexylidene]hydrazinecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(R)-5-Methyl-2-(1-methylethylidene)cyclohexylidene]hydrazinecarboxamide(23733-71-3)
• EPA Substance Registry System: 2-[(R)-5-Methyl-2-(1-methylethylidene)cyclohexylidene]hydrazinecarboxamide(23733-71-3)

Safety Data

• Hazardous Substances Data: 23733-71-3(Hazardous Substances Data)

Upstream product

• 89-82-7 pulegone 
• 563-41-7 semicarbazide hydrochloride 

Downstream Products

• 89-82-7 pulegone 
• 139943-22-9 (3R)-2-(2-Cyanoethyl)-6-isopropylidene-3-methylcyclohexanone 
• 56021-79-5 N-((3R)-6-isopropylidene-3-methyl-1-cyclohexenyl)pyrrolidine 

Relevant articles and documents

Ruthenium-Catalyzed Hydration of Nitriles and Transformation of δ-Ketonitriles to Ene-lactams: Total Synthesis of (-)-Pumiliotoxin C

Hydration of nitriles with 1-2 equivalents of water can be performed efficiently by using RuH2(PPh3)4 catalyst to give the corresponding amides.Under the similar reaction conditions, δ-ketonitriles can be converted into the corresponding ene-lactams, which are versatile synthetic intermediates.The efficiency of the reaction is demonstrated by the short-step synthesis of (-)-pumiliotoxin C.