237435-27-7

Basic information

• Product Name: ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate
• Synonyms: ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate
• CAS NO: 237435-27-7
• Molecular Formula: C₁₃H₁₄N₂O₂
• Molecular Weight: 230.26246
• Mol File: 237435-27-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 152-153°
• Boiling Point: 459.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.213±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.89±0.50(Predicted)
• CAS DataBase Reference: ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate(237435-27-7)
• EPA Substance Registry System: ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate(237435-27-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 237435-27-7(Hazardous Substances Data)

Usage

Description

Ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate is an organic compound with a unique chemical structure that features a pyrrole ring and an ester functional group. It is known for its potential applications in various fields due to its specific properties and reactivity.

Uses

Used in Pharmaceutical Industry:
Ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate is used as an inhibitor of interleukin-1β-converting enzyme (ICE) for its anti-inflammatory properties. By inhibiting ICE, it can help regulate the immune response and potentially treat conditions associated with excessive inflammation.
Used in Research Applications:
In the field of scientific research, ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate serves as a valuable compound for studying the mechanisms of inflammation and the role of interleukin-1β in various diseases. Its use as an ICE inhibitor can provide insights into the development of new therapeutic strategies for inflammatory disorders.
Used in Drug Development:
Ethyl 3-amino-5-phenyl-1H-pyrrole-2-carboxylate can be utilized in the development of new drugs targeting inflammatory conditions. Its ICE inhibitory activity makes it a promising candidate for the creation of novel pharmaceuticals that can help manage and treat a range of inflammatory diseases, including autoimmune disorders and chronic inflammatory conditions.

Upstream product

• 13433-00-6 diethyl aminomalonate hydrochloride 
• 237435-26-6 2-cyano-1-phenylvinyl-4-methylbenzenesulfonate 
• 614-16-4 Benzoylacetonitrile 

Downstream Products

• 34771-39-6 6-phenylpyrrolo[3,2-d]pyrimidine-2,4-diol 
• 237435-70-0 6-phenyl-2-propylpyrrolo[3,2-d]pyrimidin-4-ol 
• 237435-78-8 2-(2-methyl propyl)-6-phenylpyrrolo[3,2-d]pyrimidin-4-ol 
• 237435-53-9 6-phenyl-2-(trifluoromethyl)pyrrolo[3,2-d]pyrimidine-4-ol 
• 237435-30-2 6-phenyl-2-sulfanylpyrrolo[3,2-d]pyrimidin-4-ol 
• 237435-34-6 2-cyclopropyl-6-phenylpyrrolo[3,2-d]pyrimidine-4-ol 
• 313950-09-3 tert-butyl 2-aza-3-[(tert-butoxy)carbonylamino]-3-{[2-(ethoxycarbonyl)-5-phenylpyrrol-3-yl]amino}prop-2-enoate 
• 237435-32-4 2-ethyl-6-phenylpyrrolo[3,2-d]pyrimidine-4-ol 
• 850145-21-0 N-(2-chloroethyl)-N'-[3-(2-ethoxycarbonyl-5-phenyl)-1H-pyrrolyl]urea 
• 850145-22-1 N-(3-chloropropyl)-N'-[3-(2-ethoxycarbonyl-5-phenyl)-1H-pyrrolyl]urea 
• 866925-42-0 8-oxo-2-phenyl-5,6,7,8-tetrahydro-1H-1,4,7a-triaza-s-indacene-7-carboxylic acid ethyl ester 
• 237435-80-2 2,4-dichloro-6-phenylpyrrolo[3,2-d]pyrimidine 
• 237435-33-5 4-chloro-2-ethyl-6-phenylpyrrolo[3,2-d]pyrimidine 

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